超声引导下经皮射频消融治疗多囊肝病的有效性及安全性  

Efficacy and safety of ultrasound-guided percutaneous radiofrequency ablation in treatment of polycystic liver disease

作　　者：张姗姗[1] 董刚[1] 孙璐璐[1] 任志刚[2] 纪晓惠[3] 吴洁[1] 刘婷婷[1] 彭梦凡 ZHANG Shanshan;DONG Gang;SUN Lulu;REN Zhigang;JI Xiaohui;WU Jie;LIU Tingting;PENG Mengfan(Department of Ultrasound,the First Affiliated Hospital of Zhengzhou University,Zhengzhou 450052,China;Department of Infection,the First Affiliated Hospital of Zhengzhou University,Zhengzhou 450052,China;Department of Ultrasound,the Fourth Hospital of Hebei Medical University,Shijiazhuang 050011,China)

机构地区：[1]郑州大学第一附属医院超声科,河南郑州450052 [2]郑州大学第一附属医院感染科,河南郑州450052 [3]河北医科大学第四医院超声科,河北石家庄050011

出　　处：《中国介入影像与治疗学》2020年第12期711-714,共4页Chinese Journal of Interventional Imaging and Therapy

基　　金：河南省医学科技攻关计划项目(201702037);河南省高等学校重点科研计划项目(19B320016)。

摘　　要：目的观察超声引导下经皮射频消融(RFA)治疗多囊肝病(PLD)的有效性及安全性。方法回顾性分析14例接受超声引导RFA治疗的PLD患者,观察术后症状改善及并发症情况;比较术前与术后1周肝功能及术前与术后12个月肝内囊肿总体积。结果14例中,13例顺利完成RFA,1例因术中出血而中止治疗;术后即刻患者腹胀较术前明显好转,术后1周症状明显缓解率92.31%(12/13);术中及术后未见严重不良反应。术前与术后1周丙氨酸转氨酶(ALT)、天冬氨酸转氨酶(AST)及总胆红素(TBIL)水平差异均无统计学意义(P>0.05)。术后12个月肝内囊肿总体积较术前显著缩小(P<0.05)。结论超声引导下经皮RFA治疗PLD效果较好,且安全性较高。Objective To observe the efficacy and safety of ultrasound-guided percutaneous radiofrequency ablation(RFA)in treatment of polycystic liver disease(PLD).Methods Data of 14 PLD patients treated with ultrasound-guided RFA were retrospectively analyzed,postoperative symptom improvement and complications were observed.Indexes of liver function preoperative and 1 week postoperative were compared.The total volume of intrahepatic cysts before and 12 months after operation were compared.Results Among 14 patients,RFA was successfully completed in 13 patients,while in 1 patient was terminated due to intraoperative bleeding.Abdominal distension was significantly immediately improved,and the obvious symptom relief rate was 92.31%(12/13)1 week after operation.No serious adverse reaction was observed peri-operation.No significant difference of alanine aminotransferase(ALT),aspartate aminotransferase(AST)nor total bilirubin(TBIL)levels was observed 1 week after operation(all P>0.05).Twelve months after operation,the total volume of intrahepatic cysts was significantly smaller than that before operation(P<0.05).Conclusion Ultrasound-guided percutaneous RFA was effective and safe in treatment of PLD.

关 键 词：肝 囊肿 超声检查 射频消融 

分 类 号：R657.3[医药卫生—外科学] R445.1[医药卫生—临床医学]