剖宫产切口感染产妇的病原菌分布及药敏分析  

Pathogen distribution and drug susceptibility of patients with cesarean section incision infection

作　　者：张隆英[1] 胡妙仙 罗希[1] 林敏秀 林枫[1] 周兴辉[1] ZHANG Longying;HU Miaoxian;LUO Xi;LIN Minxiu;LIN Feng;ZHOU Xinghui(Department of Gynecology and Obstet­rics,Integrated Traditional Chinese and Western Medicine Hospital of Taizhou,Wenling 317523,Zhejiang,China)

机构地区：[1]台州市中西医结合医院妇产科,浙江温岭317523

出　　处：《中国性科学》2020年第12期76-78,共3页Chinese Journal of Human Sexuality

基　　金：浙江省温岭市科技项目(2017C311137)。

摘　　要：目的探讨剖宫产手术切口感染产妇病原菌的分布与耐药性,为控制产妇切口感染发生及合理用药提供指导。方法选取2011年1月至2017年10月于台州市中西医结合医院行剖宫产且合并感染的产妇41例作为研究对象。收集并观察产妇的临床资料、病原菌的种类、药物敏感性情况及耐药率。结果6年间产妇发生切口感染41例,浅层感染38例(92.68%),共分离到43株病原菌,主要为革兰氏阳性球菌,占72.09%,革兰氏阴性菌占27.91%。药敏显示,革兰氏阳性菌中金黄色葡萄球菌和表皮葡萄球菌耐药严重,对大多数抗生素耐药,对青霉素G完全耐药,对万古霉素100%敏感;革兰氏阴性菌中大肠埃希菌对头孢呋辛、阿米卡星、左氧氟沙星敏感性不高,对三代头孢有一定的敏感性,对亚胺培南100%敏感。结论剖宫产产妇切口感染以浅层感染为主,多为条件致病菌。分析菌株耐药性对产妇合理用药、降低感染发生率将起到重要作用。Objective To explore the distribution and drug resistance of pathogenic bacteria in incision infection of cesarean section,and to provide guidance for controlling incision infection and rational use of antibiotics.Methods 41 cases of pregnant women with incision infection of cesarean section in Integrated Traditional Chinese and Western Medicine Hospital of Taizhou from January 2011 to October 2017 were selected as the research objects,and the clinical data,types of pathogenic bacteria,drug susceptibility and drug resistance rate of pregnant women were collected and observed.Results Among the 41 cases of incision infection,38 cases(92.68%)occurred superficial infection,43 strains of pathogenic bacteria were isolated,72.09%of which are gram-positive cocci,while 27.91%are Gram-negative bacteria.Drug susceptibility tests showed that staphylococcus aureus and Staphylococcus epidermidis were highly resistant to most antibiotics,completely resistant to penicillin G and 100%sensitive to vancomycin.In gram-negative bacteria,escherichia coli has low sensitivity to cefuroxime,amikacin and levofloxacin,has certain sensitivity to third-generation cephalosporin,and is 100%sensitive to imipenem.Conclusions The incision infection of cesarean section is mainly superficial infection,and most of them are conditional pathogens.Analysis of drug resistance of the strains will play an important role to reduce the incidence of infection.

关 键 词：剖宫产 手术 切口感染 病原菌 耐药性 

分 类 号：R714[医药卫生—妇产科学]