腹腔镜术与开腹卵巢囊肿剥除术治疗卵巢囊肿的临床效果及对患者卵巢储备功能影响  

Clinical efficacy of laparoscopic and transabdominal ovarian cystectomy of women with ovarian cysts and their influence on ovarian reserve function

作　　者：刘微微 李红英[1] 冯同富[1] 姚冬梅[1] 唐静[1] 周俭珊 陈娜 LIU Weiwei;LI Hongying;FENG Tongfu;YAO Dongmei;TANG Jing;ZHOU Jinshan;CHEN Na(Hubei Maternal and Child Health Care Hospital, Wuhan, Hubei Province, 437100)

机构地区：[1]湖北省妇幼保健院,武汉437100

出　　处：《中国计划生育学杂志》2020年第11期1786-1789,共4页Chinese Journal of Family Planning

基　　金：湖北省卫生健康委科研资金(WJ2019H1188)。

摘　　要：目的:探究经腹腔镜与开腹卵巢囊肿剥除术对卵巢囊肿患者的临床疗效及对卵巢储备功能的影响。方法:选取2016年1月-2018年6月本院妇科行卵巢囊肿剥除术的卵巢囊肿患者150例,按照随机数字表法分组各75例,分别予以腹腔镜卵巢囊肿剥除术(腹腔镜组)或经腹卵巢囊肿剥除术(开腹术组)。比较两组患者抗卵巢抗体(AOAb)、抗透明带抗体(AzpAb)、抗核抗体(ANA),卵巢储备功能指标抗苗勒管激素(AMH)、卵泡刺激素(FSH)、雌二醇(E2),免疫功能指标免疫球蛋白M(IgM)、免疫球蛋白A(IgA)、免疫球蛋白G(IgG)水平及手术情况。结果:术后腹腔镜组AOAb值、AzpAb、ANA阳性率均低于开腹术组,AMH水平低于开腹术组,E2、FSH水平高于开腹术组,IgG水平低于开腹术组(均P<0.05),IgM、IgA水平两组无差异(P>0.05)。腹腔镜组手术时间、术中出血量、术后下床时间低于开腹术组(P<0.05)。结论:经腹腔镜下卵巢囊肿剥除术具有创伤小、手术时间短、术中出血量少,术后身体恢复快等优点,但开腹卵巢囊肿剥除术对患者卵巢储备功能及免疫功能影响更小,保护妇女生育功能的作用更明显。Objective:To investigate the clinical effect of laparoscopic and transabdominal ovarian cystectomy of women with ovarian cysts,and to study their influence on their ovarian reserve function.Methods:From January 2016 to June 2018,150 women with ovarian cyst underwent ovarian ovarian cystectomy were divided into control group and experimental group(75 cases in each group)according to the random number table method.Women in the control group had received transabdominal ovarian cystectomy,and women in the experimental group had received laparoscopic ovarian cystectomy.The levels of anti ovarian antibody(AOAb),anti zona pellucida antibody(AzpAb),anti nuclear antibody(ANA),and ovarian reserve function indexes,such as anti Mullerian hormone(AMH),follicle stimulating hormone(FSH),and estradiol(E2),and immune function indexes,such as immunoglobulin M(IgM),immunoglobulin A(IGA),and immunoglobulin G(IgG)),and operation situation of women were compared between the two groups.Results:After operation,the AOAb,AzpAb,and ANA levels,and the E2 and FSH levels of women in the experimental group were significant lower than those of women in the control group,but the levels of AMH and IgG of women in the experimental group were significant higher(all P<0.05).There were no significant different in IgM and IgA levels between the two groups(P>0.05).The operation time,intraoperative hemorrhage,and the time of getting out of bed of women in the experimental group were significant lower than those of women in the control group(P<0.05).Conclusion:Laparoscopic ovarian cystectomy has the advantages of fewer traumas,shorter operation time,less intraoperative bleeding,and faster recovery,but transabdominal ovarian cystectomy has less impact on ovarian reserve function with better protection for reproductive function of women.

关 键 词：卵巢囊肿 腹腔镜手术 开腹卵巢囊肿剥除术 卵巢储备功能 临床疗效 

分 类 号：R71[医药卫生—妇产科学]