奶牛乳腺炎金黄色葡萄球菌免疫逃避机制研究进展  

Research Progress on the Staphylococcus aureus Immune Evasion in Bovine Mastitis

作　　者：刘丹丹[1] 崔常勇 张弛 刘明江[1,3] LIU Dandan;CUI Changyong;ZHANG Chi;LIU Mingjiang(College of Veterinary Medicine,Yangzhou University,Yangzhou 225009,China;Long Kou Customhouse,Yantai 265700,China;Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses,Yangzhou 225009,China)

机构地区：[1]扬州大学兽医学院,扬州225009 [2]龙口海关,烟台265700 [3]江苏省动物重要疫病与人畜共患病防控协同创新中心,扬州225009

出　　处：《畜牧兽医学报》2020年第12期2964-2971,共8页ACTA VETERINARIA ET ZOOTECHNICA SINICA

基　　金：国家自然科学基金(31602097);江苏省高校优势学科建设工程资助项目。

摘　　要：金黄色葡萄球菌(Staphylococcus aureus,SA)型奶牛乳腺炎是一种较难控制的慢性、亚临床型传染病,给奶牛养殖业带来巨大的经济损失。多种SA免疫逃避机制在乳腺炎发生、发展过程中起重要作用,且SA的免疫逃避机制多与菌体毒力因子相关。本文对近年研究的奶牛乳腺炎SA的免疫逃避机制进行了综述,以期为SA型奶牛乳腺炎的防治研究提供参考。Staphylococcus aureus(SA)bovine mastitis is a chronic and subclinical infectious disease,which is hard to control.It brings unpredictable losses to dairy-farming industry.Immune escape effect of SA plays an important role in the occurrence and development of mastitis,and some virulence factors are mostly associated with the immune evasion of bacteria.In this paper,some important immune evasion mechanisms of SA in recent researches were reviewed in order to provide theoretical reference for further prevention and treatment of mastitis in dairy cows.

关 键 词：奶牛乳腺炎 金黄色葡萄球菌 免疫逃避 

分 类 号：S855.1[农业科学—临床兽医学]