超声造影对大于3 cm的HCC及ICC的鉴别价值研究  

Study on differential value of contrast enhanced ultrasonography in HCC and ICC>3 cm

作　　者：罗水莲 吴猛[1] LUO Shuilian;WU Meng(Department of Ultrasound Imaging,Zhongnan Hospital of Wuhan University,Wuhan,Hubei 430071,China)

机构地区：[1]武汉大学中南医院超声影像科,武汉430071

出　　处：《重庆医学》2020年第24期4116-4119,共4页Chongqing medicine

基　　金：武汉大学中南医院面上培育基金(znpy2018021)。

摘　　要：目的探讨超声造影鉴别大于3 cm的原发性肝细胞性肝癌(HCC)和肝内胆管细胞癌(ICC)的临床价值。方法收集该院行常规超声及超声造影检查并经手术或超声引导下穿刺活检病理证实为HCC和ICC的患者,对比两组患者超声造影特点,评估超声定量分析在两者的鉴别诊断中的运用价值。结果在超声造影模式上,两组患者均表现为“快进快出”模式。在动脉期增强模式中,两组患者均存在多种增强模式,但差异无统计学意义(P>0.05)。在超声造影定量分析中,HCC与ICC的开始增强时间、上升时间、达峰时间及开始廓清时间的比较,差异均无统计学意义(P>0.05)。ICC平均渡越时间少于HCC,差异有统计学意义(P<0.05)。结论对于大于3 cm的单发病灶,平均渡越时间的差异对HCC和ICC患者具有重要的鉴别诊断价值。Objective To explore the clinical value of contrast enhanced ultrasound imaging in the differential diagnosis of primary hepatocarcinoma(HCC)and intrahepatic cholangiocarcinoma(ICC).Methods The patients with HCC and ICC confirmed by operation or ultrasound guided puncture biopsy pathology in our hospital were collected.The characteristics of contrast enhanced ultrasound imaging were compared between the two groups,and the application value of quantitative ultrasound analysis between the differential diagnosis of HCC and ICC was evaluated.Results In contrast enhanced ultrasound mode,the patients of both groups showed"fast in and fast out"mode.In the arterial phase enhancement mode,there were many enhancement modes in both groups,but the difference had no statistical significance(P>0.05).In the quantitative analysis of contrast enhanced ultrasound imaging,there was no statistically significant difference in the initial enhancement time,ascending time,peak time and initial clearance time between HCC and ICC(P>0.05).The average transit time of ICC was less than that of HCC,and the difference was statistically significant(P<0.05).Conclusion For single lesion larger than 3 cm,the difference of mean transit time has important value in differential diagnosis between ICC and HCC.

关 键 词：超声检查 多普勒 彩色 血管造影术 胆管肿瘤 癌 肝细胞 诊断 鉴别 

分 类 号：R445.1[医药卫生—影像医学与核医学]