乌鲁木齐市慢性呼吸系统疾病患者糖脂代谢水平与体质量指数的相关性  

Correlation between glucose and lipid metabolism and body mass index in patients with chronic respiratory diseases in Urumqi

作　　者：裴华莲 符文慧[1] 田恬[1] 张泽文[1] 罗涛[1] 戴江红 PEI Hua-lian;FU Wen-hui;TIAN Tian;ZHANG Ze-wen;LUO Tao;DAI Jiang-hong(School of Public Health,Xinjiang Medical University,Urumqi,Xinjiang 830054,China;The First Affiliated Hospital of Xinjiang Medical University,Urumqi,Xinjiang 830054,China)

机构地区：[1]新疆医科大学公共卫生学院,新疆乌鲁木齐830054 [2]新疆医科大学第一附属医院,新疆乌鲁木齐830054

出　　处：《上海预防医学》2020年第10期810-815,共6页Shanghai Journal of Preventive Medicine

基　　金：国家重点研发计划项目;西北区域自然人群队列研究(SQ2017YFSF090013)子课题;新疆多民族自然人群队列研究及健康随访研究(2017YFC0907203)。

摘　　要：【目的】调查不同体质量指数(BMI)的慢性呼吸系统疾病患者血糖、血脂水平及代谢异常现状,探讨糖脂代谢与BMI的相关性。【方法】在“新疆多民族自然人群队列研究”乌鲁木齐市基线调查人群中,对慢性支气管炎、肺气肿与慢性阻塞性肺疾病(COPD)疾病史进行调查,并以BMI界定分为消瘦组、正常组、超重组及肥胖组,比较4组患者空腹血糖、血脂水平及代谢异常检出率。【结果】2018年乌鲁木齐市队列研究基线调查人群共6046人,其中慢性呼吸系统疾病患者545例。不同年龄段及不同体力活动水平人群慢性呼吸系统疾病患病率存在差异,消瘦组患病率明显高于其他3组。而不同性别、民族、文化程度及是否吸烟人群的患病率差异无统计学意义。空腹血糖、血清胆固醇(TC)、血清高密度脂蛋白(HDL-C)水平在慢性呼吸系统疾病不同BMI患者中差异具有统计学意义(P<0.05)。高血糖、三酰甘油(TG)偏高、HDL-C偏低检出率随BMI的升高而升高,多因素分析结果显示血糖、TG、HDL-C是BMI的影响因素。【结论】慢性呼吸系统疾病患者BMI增高与血糖脂代谢异常有关,应密切关注长期疾病患者的BMI及其营养状况,及时采取干预措施,以延缓疾病进程。[Objective]To determine the relationship between abnormal blood glucose and lipid levels and body mass index in patients with chronic respiratory diseases.[Methods]This research was conducted in Urumqi baseline survey population from“Xinjiang multi-ethnic cohort study”in which patients with chronic bronchitis,emphysema and chronic obstructive pulmonary disease(COPD)were screened.The patients were defined as angular,normal,overweight,obesity groups according to body mass index(BMI),and were compared with blood levels of lipid and glucose,and rate of abnormal metabolism.[Results]A total of 6046 subjects were included in the 2018 Urumqi cohort study,including 545 patients with chronic respiratory diseases.The prevalence of chronic respiratory diseases in different age groups and at different physical activity levels was different,and the prevalence of emaciation group was significantly higher than that of the other three groups.However,there were no statistically significant differences among people with different genders,nationalities,educational levels and whether they smoked or not.There were statistically significant differences in fasting glucose,serum cholesterol(TC)and serum high-density lipoprotein(HDL)levels among respiratory patients with different BMI(P<0.05).The detection rates of hyperglycemia,high TG and low HDL increased with the increase of BMI.The result of multi-factor analysis showed that blood glucose,TG and HDL were the influencing factors of BMI.[Conclusion]Increase of body mass index in patients with chronic respiratory diseases is associated with abnormal glucose and lipid metabolism,which is not significantly different from that in patients with non-respiratory diseases.However,the body mass index and nutritional status of patients with long-term diseases should be closely monitored,and timely intervention measures should be taken to delay the disease process.

关 键 词：呼吸 体质量指数 糖脂代谢 

分 类 号：R562[医药卫生—呼吸系统]