老年动脉粥样硬化性疾病发病机制研究  

Research on the pathogenesis of atherosclerosis diseases in the elderly

作　　者：王小娟 赵园园[1] 李大鹤[1] 张小波[1] 于俊民[1] WANG Xiao-juan;ZHAO Yuan-yuan;LI Da-he;ZHANG Xiao-bo;YU Jun-min(Department of Geriatrics Ward,the Fourth Affiliated Hospital of Harbin Medical University,Harbin 150001 China)

机构地区：[1]哈尔滨医科大学附属第四医院老年病科,黑龙江省哈尔滨市150001

出　　处：《中国心血管病研究》2020年第12期1143-1147,共5页Chinese Journal of Cardiovascular Research

基　　金：黑龙江省自然科学基金(H201389);哈尔滨医科大学附属第四医院特别资助项目(HYDSYTB201924)。

摘　　要：伴随人口老龄化加速,高龄老年人口比重增加,动脉粥样硬化性疾病致死致残率逐年增高.动脉粥样硬化是各种动脉粥样硬化性疾病的共同病理基础,发病机制复杂,涉及慢性炎症、内皮损伤、血脂代谢紊乱等过程,目前研究发现遗传、血流动力学和免疫等因素亦参与动脉粥样硬化形成.With the acton of population aing,the propoton of eldoely pouation has incated and the morali rate of aorotlecotoi discscs has also incresed year by yer.Aherososcroos is the commn pathologia basis of various arorlesotoi dsecs The mechanim is complxe,ivoving proces such as echroni iflamation,endohelial injure and Iipid metabolism disorders.Curent studies have found that genetics,hemodymamnis and immwne system are also inove in the frmatio of aeroselctois.

关 键 词：动脉粥样硬化 炎症 脂质代谢紊乱 遗传 血流动力学 

分 类 号：R543.5[医药卫生—心血管疾病]