氧化偶氮苯类化合物合成研究进展  

Progress in the Synthesis of Azoxybenzene Compound

作　　者：黄子安 李陵岚[2] 刘辉[1] HUANG Zi-an;LI Ling-lan;LIU Hui(School of Materials Science and Engineering,Wuhan Institute of Technology,Wuhan 430205,China;College of Chemistry and Chemical Engineering,Hubei University,Wuhan 430062,China)

机构地区：[1]武汉工程大学材料科学与工程学院,湖北武汉430205 [2]湖北大学化学化工学院,湖北武汉430062

出　　处：《化学试剂》2020年第11期1318-1326,共9页Chemical Reagents

基　　金：湖北省教育厅科学研究计划项目(D20181507);武汉工程大学科学研究基金项目(K201509,K201805)。

摘　　要：氧化偶氮苯化合物作为一类有机化工原料和中间体在染料、指示剂及液晶材料等方面具有重要的应用。工业上常采用葡萄糖等还原剂在碱性条件下还原芳香硝基化合物来制备氧化偶氮苯化合物,但该方法存在环境不友好的问题。简述了氧化偶氮苯化合物的发展现状,介绍了芳香硝基化合物还原和芳香氨基化合物氧化两条反应路线制备氧化偶氮苯化合物的相关研究,分析了两条合成路线的反应机理,讨论了催化体系和反应条件对选择性制备氧化偶氮苯的影响因素,总结了各种催化体系的优缺点,指出氧化偶氮苯合成方法应进一步发展高效、廉价的催化体系,发展无溶剂或以离子液体为溶剂的合成方法和以光电等新能源驱动反应的合成方法,以实现氧化偶氮苯合成反应体系更加高效、绿色、经济和简便。As a kind of organic chemical raw material and intermediate,azoxybenzene compound has important applications in dye,indicator and liquid crystal materials.In industry,the reduction of aromatic nitro compound with glucose or other reducing agents under alkaline conditions is often used to prepare azoxybenzene compound.However,the method is not environmentally friendly.The development of azoxybenzene compound was reviewed,two reaction routes of reduction of aromatic nitro compound and oxidation of aromatic amino compound to prepare azoxybenzene compound was introduced,and the reaction mechanism of two synthetic routes was analyzed.Also,the influence factors of catalytic system and reaction conditions on the selective preparation of azoxybenzene compound was discussed,and the advantages and disadvantages of various catalytic systems was summarized.It is pointed out combined with the above that the synthesis method of azoxybenzene compound should be further developed with high efficiency and low cost catalytic system,solvent-free or ionic liquid as solvent and photoelectric new energy driven reaction,so as to realize the synthesis reaction system more efficient,green,economic and simple.

关 键 词：氧化偶氮苯化合物 芳香硝基化合物 芳香氨基化合物 还原 氧化 

分 类 号：TQ61[化学工程—精细化工]