男性杓状软骨钙化对喉接触性肉芽肿治疗效果的影响  

Arytenoid cartilage calcification on the therapeutic effect of laryngeal contact granuloma in male patients

作　　者：聂倩 李进让 张冉[1] 邹世桢 NIE Qian;LI Jinrang;ZHANG Ran;ZOU Shizhen(Department of Otorhinolaryngology Head and Neck Surgery,the Sixth Medical Center of PLA General Hospital,Beijing 100089,China)

机构地区：[1]解放军总医院第六医学中心耳鼻咽喉头颈外科,北京100089

出　　处：《中国耳鼻咽喉颅底外科杂志》2020年第6期682-685,共4页Chinese Journal of Otorhinolaryngology-skull Base Surgery

摘　　要：目的研究杓状软骨钙化对喉接触性肉芽肿治疗效果的影响。方法对临床资料完整的115例喉接触性肉芽肿男性患者进行回顾性分析,统计患侧杓状软骨钙化对治疗效果的影响。结果115例男性喉接触性肉芽肿患者,年龄22~68岁,平均年龄45.82岁。其中单侧肉芽肿110(110/115,95.65%),双侧肉芽肿5例(5/115.35%);病因中有反流病史67例(67/115,58.26%),插管诱发5例(5/115,4.35%),其余患者无明显原因。115例男性患者CT显示杓状软骨伴钙化102例(102/115,88.70%),杓状软骨无钙化13例(13/115;11.30%)。其中杓状软骨伴钙化患者治愈时间>3个月68例,治愈时间≤3个月34例;杓状软骨无钙化治愈时间>3个月患者4例,治愈时间≤3个月9例。通过Chi-square检验分析显示患者杓状软骨伴钙化的治愈时间>3个月的百分数明显多于不伴钙化组(χ2=4.906,P=0.027)。结论喉接触性肉芽肿患者,杓状软骨钙化的患者治疗时间较长,可能是由于这类患者长期慢性炎性刺激引起杓状软骨钙化,病程相对较长,治疗困难。Objective To investigate the arytenoid cartilage calcification on the therapeutic effect of laryngeal contact granuloma in male patients.Methods Clinical data of 115 male patients with laryngeal contact granuloma were analyzed retrospectively,and the effect of arytenoid cartilage calcification on the therapeutic outcome was analyzed.Results The patients’age ranged from 22 to 68 years old with an average of 45.82.Of them,the granuloma was unilateral in 110 cases(95.65%,110/115)and bilateral in 5(4.35%,5/115).As for the etiology,67 cases had a history of laryngopharyngeal reflux(58.26%,67/115),5 cases were induced by endotracheal intubation(5/115%,4.35%),and the rest had no apparent causes.Laryngeal computed tomography(CT)of all the cases confirmed arytenoid cartilage calcification in 102(88.70%,102/115).Among the 102 cases with arytenoid cartilage calcification,the case number with cure time>3 months was 68,and that≤3 months was 34.Of the 13 patients without calcification,the case numbers were 4 and 9 respectively.The percentage of patients with cure time>3 months in arytenoid cartilage calcification group was significantly higher than that in the group without calcification(χ2=4.906,P=0.027).Conclusion The reason for long treatment time of the laryngeal contact granuloma patients with arytenoid cartilage calcification may be the arytenoid cartilage calcification caused by chronic inflammatory stimulation with relatively long course of disease and difficulty in treatment.

关 键 词：喉接触性肉芽肿 杓状软骨 钙化 治疗效果 

分 类 号：R767.1[医药卫生—耳鼻咽喉科]