新型磺酸功能化离子液体催化1,2,3,9-四氢咔唑-4-酮的绿色合成  

Green synthesis of 1,2,3,9-tetrahydrocarbazole-4-one catalyzed by novel sulfonic acid functionalized ionic liquids

作　　者：孙学军[1] 曹子平[1] 张淑芳[1] 周正宇 付惠 无 Sun Xuejun;Cao Ziping;Zhang Shufang;Zhou Zhengyu;Fu Hui;无(School of Chemistry and Chemical Engineering,Qufu Normal University,,Shandong,Qufu 273165;State Key laboratory of Heavy Oil Processing,College of Science,China University of Petroleum,Shandong,Qingdao 266580)

机构地区：[1]曲阜师范大学化学与化工学院,山东曲阜273165 [2]中国石油大学理学院重油加工国家重点实验室,山东青岛266580

出　　处：《云南化工》2020年第12期123-126,129,共5页Yunnan Chemical Technology

基　　金：山东省自然科学基金ZR2018MB014资助。

摘　　要：双磺酸型离子液体[(HSO3-p)2im][HSO4]催化条件下以水做溶剂,苯肼与1,3-环己二酮反应,合成1,2,3,9-四氢咔唑-4-酮的绿色合成体系,成功合成了化合物1,2,3,9-四氢咔唑-4-酮,收率为56.5%。对离子液体催化剂的重复使用情况进行了研究,离子液体重复使用6次,仍能催化合成反应,产率大于53.4%。1,2,3,9-tetrahydrocarbazole-4-one was synthesized by the reaction of phenylhydrazine with 1,3-cyclohexanedione in water as solvent under the catalysis of Bisulfonic ionic liquid[(hso3-p)2IM][HSO4].Compound 1,2,3,9-tetrahydrocarbazole-4-one was successfully synthesized in 56.5%yield.The repeated use of ionic liquid catalyst was studied.The ionic liquid can still catalyze the synthesis reaction after 6 times of reuse,and the yield is more than 53.4%.

关 键 词：离子液体 绿色合成 催化 1 2 3 9-四氢咔唑-4-酮 

分 类 号：O621.251[理学—有机化学] O645.1[理学—化学]