万应膏外敷联合手术治疗浆细胞性乳腺炎30例疗效观察  

Observation on clinical efficacy of 30 cases of Wanying ointment combined with surgery in treatment of plasma cell mastitis

作　　者：付豹[1] 王进峰[1] 刘晓飞[1] 石鹏[1] 王淑卫[1] 陈小贺[1] FU Bao;WANG Jinfeng;LIU Xiaofei;SHI Peng;WANG Shuwei;CHEN Xiaohe(General Surgery Department,Shijiazhuang Hospital of Traditional Chinese Medicine,Shijiazhuang,Hebei 050004,China)

机构地区：[1]石家庄市中医院普外科,河北石家庄050004

出　　处：《安徽医药》2021年第1期64-67,共4页Anhui Medical and Pharmaceutical Journal

基　　金：河北省中医药管理局科研计划项目(2019449)。

摘　　要：目的观察万应膏外敷联合手术治疗浆细胞性乳腺炎(PCM)的临床疗效。方法选取石家庄市中医院2017年5月至2018年3月诊治的60例PCM病人并按照随机数字表法划分成对照组和治疗组,每组各30例。对照组单一应用手术治疗,治疗组采取万应膏外敷联合手术治疗。对比两组临床疗效、中医症状体征积分、血常规、炎性因子水平及复发情况。其中临床疗效与复发情况用%表示,组间比较以χ~2检验;中医症状体征积分、血常规、炎性因子水平用■±s表示,以t检验,当P<0.05时,表示差异有统计学意义。结果治疗后,治疗组总有效率93.33%较对照组70.00%优(P<0.05);两组中医各症状体征积分、白细胞(WBC)计数及C-反应蛋白(CRP)、白细胞介素-6(IL-6)、肿瘤坏死因子α(TNF-α)水平[(7.22±1.39)、(6.52±1.05)×10~9/L,(5.46±2.30)、(3.18±1.93)mg/L,(34.62±2.85)、(26.24±2.29)ng/L,(50.21±4.54)、(41.19±3.50)ng/L]与治疗前[(8.13±1.74)、(8.07±1.58)×10~9/L,(8.84±3.26)、(8.71±3.02)mg/L,(44.25±3.39)、(43.61±3.14)ng/L,(72.51±6.47)、(71.68±5.49)ng/L]相比均有改善(P<0.05),且治疗组改善情况均优于对照组(P<0.05);治疗组复发率3.33%较对照组20.00%低(P<0.05)。结论对PCM病人采用万应膏外敷联合手术治疗,其临床疗效优于单用手术治疗,可显著降低中医症状体征积分,有效改善血常规及炎症因子水平,并大大降低疾病复发率。Objective To observe the clinical effect of Wanying Ointment combined with surgery in the treatment of plasma cell mastitis(PCM).Methods 60 PCM patients treated in Shijiazhuang Hospital of Traditional Chinese Medicine from May 2017 to March 2018 were selected and divided into control group and treatment group according to random number table method,30 cases in each group.The control group was treated with surgery alone,while the treatment group was treated with Wanying ointment combined with surgery.The clinical efficacy,TCM symptom and sign score,blood routine,inflammatory factor level and recurrence of the two groups were compared.The clinical efficacy and recurrence were expressed by’%’and the comparison between groups was tested.The scores of symptoms and signs,blood routine and inflammatory factors in TCM were expressed by(■±s)and t test,when P<0.05,the difference was statistically significant.Results After treatment,the total effective rate of the treatment group was93.33%,better than that of the control group 70%(P<0.05).The score of symptoms and signs,white blood cell(WBC),C-reactive protein(CRP),interleukin 6(IL-6),tumor necrosis factor-α(TNF-α)in the two groups[(7.22±1.39)×109/L(6.52±1.05)×10~9/L,(5.46±2.30)mg/L(3.18±1.93)mg/L,(34.62±2.85)ng/L(26.24±2.29)ng/L,(50.21±4.54)ng/L(41.19±3.50)ng/L]were improved compared with those before treatment[(8.13±1.74)×10~9/L(8.07±1.58)×109/L,(8.84±3.26)mg/L(8.71±3.02)mg/L,(44.25±3.39)ng/L(43.61±3.14)ng/L,(72.51±6.47)ng/L(71.68±5.49)ng/L](P<0.05),and the improvement in the treatment group was better than that in the control group(P<0.05).The recurrence rate of the treatment group was 3.33%,which was lower than 20.00%of the control group(P<0.05).Conclusion Wanying ointment combined with surgery for PCM patients has better clinical effect than surgery alone,it can significantly reduce TCM symptoms and signs,effectively improve blood routine and inflammatory factor levels,and greatly reduce the recurrence rate of the disease.

关 键 词：乳腺炎 浆细胞 软膏 中草药 引流术 外敷 万应膏 炎性因子 复发 

分 类 号：R655.8[医药卫生—外科学]