2019-nCoV特异性抗体在新型冠状病毒感染检测中的应用价值  

Application Value of 2019-nCoV Specific Antibody in Novel Coronavirus Infection

作　　者：马蓓洁 贾同乐 戴冬雪[1] 郝亚茹 韩梦思[1] 孙洋 杨松[1] 蔡会欣[1] MA Bei-jie;JIA Tong-le;DAI Dong-xue;HAO Ya-ru;HAN Meng-si;SUN Yang;YANG Song;CAI Hui-xin(Department of Medical Laboratory,The First Central Hospital of Baoding City,Baoding,Hebei 071000,China)

机构地区：[1]保定市第一中心医院医学检验科,河北保定071000

出　　处：《河北北方学院学报（自然科学版）》2021年第2期45-48,50,共5页Journal of Hebei North University:Natural Science Edition

摘　　要：《新型冠状病毒肺炎诊疗方案(试行第七版)》新增血清学抗体检测作为疑似病例的诊断方法。抗体检测具有采样方便、快速高效、高敏感性和高特异性的特点,与RT-PCR核酸检测互为补充,两者联合使用可显著提高不同病程COVID-19患者诊断的敏感性。综述了新型冠状病毒肺炎抗体检测的相关研究进展,探讨了2019-nCoV特异性抗体的应用价值,以期为后续抗体检测技术的临床应用及进一步研究提供参考。The diagnosis and treatment scheme for novel coronavirus pneumonia(7th Edition)adds serological antibody detection as a diagnostic method for suspected cases.Antibody detection has the characteristics of convenient sampling,high efficiency,high sensitivity and specificity,and is complementary to RT-PCR nucleic acid detection.The combination of antibody detection and RT-PCR nucleic acid detection can significantly improve the diagnosis sensitivity of COVID-19 patients with different courses of disease.This paper reviews the novel coronavirus pneumonia antibody detection research progress,and discusses the application value of 2019-nCoV specific antibody,in order to provide reference for the follow-up application and further research of antibody detection technology.

关 键 词：新型冠状病毒 新型冠状病毒肺炎 特异性抗体 核酸检测 

分 类 号：R563.1[医药卫生—呼吸系统]