肺炎支原体感染与川崎病发病机制的相关性研究  

Study on the correlation between mycoplasma pneumoniae infection and the pathogenesis of Kawasaki disease

作　　者：姚家会[1] 彭刚[1] 游德敏[1] 郑学琴 Yao Jiahui;Peng Gang;You Demin;Zheng Xueqin(Department of Pediatrics,Guizhou Aerospace Hospital,Guizhou Zunyi 563000)

机构地区：[1]贵州航天医院儿科,贵州遵义563000

出　　处：《中国社区医师》2020年第36期62-63,共2页Chinese Community Doctors

基　　金：遵义市科学技术局市院联合基金项目,遵市科合社字[2018]109号。

摘　　要：目的:探讨肺炎支原体感染与川崎病发病机制之间的关系。方法:选取2018年11月-2019年5月川崎病患儿35例与呼吸道感染患儿127例,对比肺炎支原体感染阳性率;将川崎病患儿分为阳性组与阴性组,分析肺炎支原体感染与川崎病发病机制的关系。结果:35例川崎病患儿中,肺炎支原体感染9例,阳性率为25.71%;127例呼吸道感染患儿中,肺炎支原体感染15例,阳性率为11.81%;川崎病患儿的阳性率高于肺炎支原体感染患儿,差异有统计学意义(P<0.05)。川崎病患儿中,阳性患儿的血小板率(PLT)及热程均高于阴性患儿,差异有统计学意义(P<0.05)。结论:肺炎支原体感染与川崎病的发病有密切关系,有可能是导致川崎病发病的原因,还可以导致患儿出现其他并发症。Objective:To investigate the relationship between mycoplasma pneumoniae infection and the pathogenesis of Kawasaki disease.Methods:From November 2018 to May 2019,35 cases of children with Kawasaki disease and 127 cases of children with respiratory tract infection were enrolled,to compare the positive rate of mycoplasma pneumoniae infection and to divide Kawasaki disease into positive group and negative group.Results:Of 35 cases of children with Kawasaki disease,9 cases had mycoplasma pneumoniae infection,the positive rate was 25.71%.Of 127 cases of children with respiratory tract infection,15 cases were infected with mycoplasma pneumoniae,the positive rate was 11.81%.The positive rate of mycoplasma pneumoniae infection in Kawasaki disease was higher than that in mycoplasma pneumoniae infection,the difference was statistically significant(P<0.05).Among the children with Kawasaki disease,the platelet rate(PLT)and thermal process of positive children were higher than those of negative children,the differences were statistically significant(P<0.05).Conclusion:Mycoplasma pneumoniae infection is closely related to Kawasaki disease,which may be the cause of Kawasaki disease and other complications.

关 键 词：肺炎支原体 川崎病 发病机制 感染 

分 类 号：R725.6[医药卫生—儿科] R725.4[医药卫生—临床医学]