阿尔茨海默病中医证候诊断标准研究进展  

Research progress on diagnostic criteria of TCM syndromes in Alzheimer’s disease

作　　者：周茜 傅勤慧[1] 裴建[1] ZHOU Qian;FU Qinhui;PEI Jian(Department of Acupuncture,Longhua Hospital Affiliate to Shanghai University of Traditional Chinese Medicine,Shanghai 200032,China)

机构地区：[1]上海中医药大学附属龙华医院针灸科,上海200032

出　　处：《上海中医药杂志》2020年第12期91-96,共6页Shanghai Journal of Traditional Chinese Medicine

基　　金：国家自然科学基金项目(81603697);上海市科委重点科研项目(16401970300,18401970500);上海市卫健委海派中医流派“陆氏针灸”传承研究项目[ZY(2018-2020)-CCCX-1006];上海市卫健委中医药新兴交叉学科资助计划建设项目(Shxxjcxk201709);上海市卫健委中医重点专科培育项目(Shzjzk201906)。

摘　　要：综述近年来阿尔茨海默病(AD)中医证候分布规律研究进展,并对AD中医证候诊断标准的规范化研究进行回顾和展望。AD临床多表现为本虚标实、虚实夹杂的复杂证候。虚证可见肾虚、心虚,实证可见痰浊、血瘀等。以标准规范的证候要素为基础,具有中医特色的AD诊断标准及证候量表已使用于临床。AD的生物学研究可为中医证候微观辨证提供科学依据,同时有助于将宏观辨证和微观辨证有机结合,进而制定出与AD整个病理发展过程相适应的证候诊断标准。This article reviews the current distribution of TCM syndromes in Alzheimer’s disease(AD),and summarizes and discusses the standardization of diagnostic criteria for TCM syndromes in AD.The clinical manifestations of AD are mostly complex syndromes of deficient syndrome with excessive symptoms.Deficient syndrome may include kidney deficiency,heart deficiency,etc.Excessive syndrome may include phlegm turbidity,blood stasis,etc.At present,based on standardized TCM syndrome factors,the AD syndrome scale with TCM characteristics has been used in the clinic.The biological research progress of AD can provide scientific basis for microscopic differentiation of TCM syndromes,and provide research strategies for interpreting AD TCM syndrome theory.The biological research of AD will help the organic combination of macro-syndrome and micro-syndrome differentiation,and formulate the diagnostic criteria of syndromes that are compatible with the entire pathological development of AD.

关 键 词：阿尔茨海默病 中医证候 诊断标准 综述 

分 类 号：R277.7[医药卫生—中医学]