经血管内介入栓塞术治疗脑动脉瘤破裂的临床效果探析  

Clinical effect of endovascular interventional embolization in the treatment of ruptured cerebral aneurysm

作　　者：张宁[1] 杨扬 ZHANG Ning;YANG Yang(Department of Neurosurgery,First Affiliated Hospital of Baotou Medical College,Inner Mongolia University of Science and Technology,Baotou 014010,China)

机构地区：[1]内蒙古科技大学包头医学院第一附属医院神经外科,014010

出　　处：《中国实用医药》2020年第36期4-6,共3页China Practical Medicine

基　　金：国家自然科学基金(项目编号:81660214);内蒙古科技厅科技计划项目(项目编号:201702101)。

摘　　要：目的探讨采用经血管内介入栓塞术治疗脑动脉瘤(CA)破裂的临床效果。方法104例CA破裂患者,随机分为对照组和观察组,每组52例。对照组患者采用开颅夹闭术治疗,观察组患者采用经血管内介入栓塞术治疗。比较两组临床疗效、并发症发生情况、手术前后脑组织血流量(CBF)及健康调查简表(SF-36)评分。结果观察组恢复良好率为92.31%明显高于对照组的75.00%,差异具有统计学意义(P<0.05)。观察组患者的并发症发生率为5.77%明显低于对照组的21.15%,差异具有统计学意义(P<0.05)。观察组阻断颅内动脉瘤时、术后的CBF均明显低于对照组,差异具有统计学意义(P<0.05)。术后,观察组生理职能、生理功能、社会功能、精神状况、健康状况、活力、机体疼痛、情感功能评分均明显高于对照组,差异具有统计学意义(P<0.05)。结论采用经血管内介入栓塞术治疗CA破裂的临床效果显著,创伤小,对脑组织血流量影响小,并发症发生率低,有助于生活质量的提高。Objective To discuss the clinical effect of endovascular interventional embolization in the treatment of ruptured cerebral aneurysm(CA).Methods A total of 104 patients with ruptured CA were randomly divided into control group and observation group,with 52 cases in each group.The control group was treated with craniotomy and clipping,while the observation group was treated with endovascular interventional embolization.The clinical efficacy,occurrence of complications,cerebral blood flow(CBF)and 36-item short-form(SF-36)score before and after operation were compared between the two groups.Results The good recovery rate of the observation group was 92.31%,which was obviously higher than 75.00%of the control group,and the difference was statistically significant(P<0.05).The incidence of complications of the observation group was 5.77%,which was obviously lower than 21.15%of the control group,and the difference was statistically significant(P<0.05).The CBF of the observation group was significantly lower than that of the control group at the time of intracranial aneurysm occlusion and after operation,and the difference was statistically significant(P<0.05).After operation,the role-physical,physiological function,social function,mental status,health status,vitality,body pain,emotional function score of the observation group were obviously higher than those of the control group,and the difference was statistically significant(P<0.05).Conclusion Endovascular interventional embolization has rem arkable effect on ruptured CA with small trauma,less impact on cerebral blood flow,and low incidence of complications,which is helpful to improve the quality of life of patients.

关 键 词：脑动脉瘤破裂 经血管内介入栓塞术 效果 

分 类 号：R651.12[医药卫生—外科学]