瑞芬太尼联合右美托咪定在老年全麻手术患者中的效果评价  

Effect evaluation of remifentanil combined with dexmedetomidine in elderly patients undergoing general anesthesia

作　　者：王瑛 WANG Ying(Xietang Community Health Service Center of Suzhou Industrial Park,Suzhou 215123,China)

机构地区：[1]苏州工业园区斜塘社区卫生服务中心,215123

出　　处：《中国实用医药》2020年第35期24-26,共3页China Practical Medicine

摘　　要：目的探讨瑞芬太尼联合右美托咪定在老年全身麻醉(全麻)手术患者中的效果。方法 80例老年全麻手术患者作为研究对象,根据麻醉方法不同分为对照组与观察组,每组40例。对照组患者单纯使用瑞芬太尼,观察组患者采用瑞芬太尼联合右美托咪定。比较两组患者不同时刻[麻醉诱导成功后(T0)、插管时(T1)、插管后1 min(T2)、插管后5 min(T3)]血流动力学指标[平均动脉压(MAP)、血氧饱和度(SpO2)、心率(HR)]和其他手术指标(苏醒时间、拔管时间、镇静评分、躁动发生情况)。结果观察组患者T0、T1、T2、T3时MAP、SpO2、HR水平比较差异无统计学意义(P>0.05);对照组患者T0、T2、T3时MAP、SpO2、HR水平比较差异无统计学意义(P>0.05);但对照组患者T1时MAP、SpO2、HR水平均较T0时明显降低,差异均具有统计学意义(P<0.05)。两组患者苏醒时间、拔管时间比较差异无统计学意义(P>0.05);观察组镇静评分(3.87±0.82)分明显高于对照组的(1.69±0.54)分,躁动发生率2.5%低于对照组的15.0%,差异具有统计学意义(P<0.05)。结论瑞芬太尼联合右美托咪定用于老年患者全麻手术效果显著,患者血流动力学更稳定且镇痛镇静效果好,具有较高的临床价值。Objective To discuss the effect of remifentanil combined with dexmedetomidine in elderly patients undergoing general anesthesia.Methods A total of 80 elderly patients undergoing general anesthesia as study subjects were divided into control group and observation group according to different anesthesia methods,with 40 cases in each group.The control group was treated with remifentanil,and the observation group was treated with remifentanil combined with dexmedetomidine.The hemodynamic indexes[mean arterial pressure(MAP),blood oxygen saturation(SpO2),heart rate(HR)]at different time points[after successful induction of anesthesia(T0),during intubation(T1),1 min after intubation(T2),and 5 min after intubation(T3)]and other surgical indicators(wake-up time,extubation time,sedation score and occurrence of restlessness)were compared between the two groups.Results In the observation group,there was no statistically significant difference in levels of MAP and SpO2 and HR at T0,T1,T2 and T3(P>0.05).In the control group,there was no statistically significant difference in levels of MAP and SpO2 and HR at T0,T2 and T3(P>0.05).In the control group,the levels of MAP and SpO2 and HR at T1 was obviously lower than that at T0(P<0.05).There was no statistically significant difference in wake-up time and extubation time between the two groups(P>0.05).The sedation score(3.87±0.82)points of the observation group was obviously higher than(1.69±0.54)points of the control group,and incidence of restlessness 2.5%was lower than 15.0%of the control group,and the difference was statistically significant(P<0.05).Conclusion Remifentanil combined with dexmedetomidine is effective for general anesthesia in elderly patients.The hemodynamics of the patients are more stable and the analgesia and sedation effect is good.This method has high clinical value.

关 键 词：瑞芬太尼 右美托咪定 老年 全身麻醉手术 

分 类 号：R614.2[医药卫生—麻醉学]