2017—2018年北京市房山区暴露人群禽流感病毒血清学调查  

Serological survey of avian influenza virus infection among exposed population in Fangshan district of Beijing from 2017 to 2018

作　　者：田竞[1] 朱芳 崔兰梅[1] 李丽丽[1] 黄少平[1] 阚震[1] TIAN Jing;ZHU Fang;CUI Lan-mei;LI Li-li;HUANG Shao-ping;KAN Zhen(Beijing Fangshan District Center for Disease Control and Prevention,Beijing 102488,China;不详)

机构地区：[1]北京市房山区疾病预防控制中心,北京102488 [2]首都医科大学燕京医学院

出　　处：《江苏预防医学》2020年第6期621-622,628,共3页Jiangsu Journal of Preventive Medicine

基　　金：北京市优秀人才培养资助项目(2018000077606G480);北京市房山区优秀人才培养资助项目(2016000000007G002)。

摘　　要：目的了解近年北京市房山区禽类、猪类从业人员和野生候鸟栖息地附近人群禽流感病毒感染情况,为早期发现和制定有效防控措施提供科学依据。方法2017—2018年,采用整群抽样方法,选取房山区禽类、猪类从业人员和野生候鸟栖息地附近人员进行问卷调查及血清学检查,采用血凝抑制法检测禽流感血清抗体滴度。结果共调查911人,禽流感病毒抗体阳性率7.24%;2017年阳性率为9.67%,2018年为4.82%,差异有统计学意义(P<0.01)。亚型以H5最高(阳性率3.18%),其次为H9(2.64%);2017年以H5亚型为主(占54.54%),2018年以H9亚型为主(占77.27%)。暴露人群感染禽流感病毒血清学阳性率以半山区(10.39%)、禽类从业人员(9.13%)、≥50岁年龄组(7.78%)最高,不同地区、暴露和年龄组人群阳性率差异无统计学意义(P值均>0.05)。结论北京市房山区暴露人群存在感染H5、H7、H9亚型禽流感病毒的风险,应重点加强对H5和H9亚型的监测。Objective To understand the infection situation of avian influenza virus(AIV)among poultry and swine practitioners together with population near wild migratory birds habitats in Fangshan district of Beijing in recent years;to provide scientific basis for early detection and formulation of effective prevention and control measures.Methods From 2017 to 2018,a cluster sampling method was used to select poultry and swine practitioners together with population near wild migratory birds habitats in Fangshan district for questionnaire survey and serological examination,the hemagglutination inhibition method was used to detect the serum AIV antibody titer.Results A total of 911 subjects were investigated,the AIV antibody positive rate was 7.24%.The AIV antibody positive rate of 2017(9.67%)was higher than that of 2018(4.82%),the difference was statistically significant(P<0.01).The H5 subtype had the highest positive rate(3.18%),followed by H9(2.64%).The major subtype was H5(accounted for 54.54%)in 2017 and H9(accounted for 77.27%)in 2018.Among all exposed populations,the serum positive rates of population in semi mountainous area(10.39%),poultry employees(9.13%),and age group≥50 years or older(7.78%)were relatively higher.However,There was no significant difference for serum positive rates among groups of different regions,exposures and age groups(all P>0.05).Conclusion There are infection risks for AIV H5,H7 and H9 subtypes in the exposed population in Fangshan district of Beijing.The surveillance of H5 and H9 subtypes should be strengthened in the future.

关 键 词：禽流感 血清学调查 暴露人群 流行病学特征 

分 类 号：R373.1[医药卫生—病原生物学]