性早熟儿童生活质量及其影响因素研究  

Study on the quality of life of children with precocious puberty and its influence factors

作　　者：杨红[1] 罗顺清[1] 唐芳[1] 曾莉[1] 程婷[1] 朱岷[2] 林琴[2] 梁小华[3] 吴迪[1] 马勤香[2] YANG Hong;LUO Shunqing;TANG Fang;ZENG Li;CHENG Ting;ZHU Min;LIN Qin;LIANG Xiaohua;WU Di;MA Qinxiang(Department of Pediatric General Medicine,Children's Hospital of Chongqing Medical University,Chongqing,400010,China)

机构地区：[1]重庆医科大学附属儿童医院内科全科病房,400010 [2]重庆医科大学附属儿童医院内分泌科,400010 [3]重庆医科大学附属儿童医院临床流行病学与生物信息学研究室

出　　处：《中国护理管理》2020年第12期1795-1800,共6页Chinese Nursing Management

基　　金：重庆医科大学附属儿童医院护理院级科研项目(CHCQMU2019.11)。

摘　　要：目的:调查性早熟儿童治疗期间生活质量现状,分析其生活质量影响因素,为提高患儿生活质量提供依据。方法:采用成组病例对照研究,匹配原则为同年龄、同性别、长期居住地为重庆。病例组为重庆市某三级甲等儿童医院门诊接受治疗的134例5~12岁的特发性中枢性性早熟儿童,同期选择在重庆市市区某两所小学就读的210例正常发育、无慢性疾病的儿童为对照组。应用一般资料调查表、儿童生存质量普适性核心量表(PedsQLTM4.0)进行调查。结果:除生理功能维度外,病例组儿童在PedsQLTM4.0量表总分及其余各维度得分明显低于对照组儿童(P<0.05),其中情感维度得分差异最大。多元回归分析显示,患儿年龄是生活质量总分、社会心理、社交功能和学校表现的影响因素;患儿照护者职业类型是情感功能、社会心理和生活质量总分的影响因素;治疗药物类型是社交功能的影响因素。结论:性早熟儿童治疗期间生活质量下降,医护人员应根据患儿年龄段和不同药物治疗方式采取针对性措施,同时加强对患儿主要照护者心理干预和健康宣教,提高性早熟儿童生活质量。Objective:To investigate the quality of life of children with precocious puberty during treatment,and to analyze the influencing factors in order to provide a reference to improve the quality of life of children.Methods:It was a case-control study with matching age and sex in patients who had long-term residence in Chongqing.The case group consisted of 134 patients with Idiopathic Central Precocious Puberty(ICPP)aged 5-12 years who were treated in a children's hospital.A total of 210 children with normal development and no chronic diseases were selected as control group from 2 schools.The participants were investigated using demographic questionnaire and PedsQLTM4.0.Results:Compared with controls,the cases had significant low quality of life score(P<0.05).Multivariate stepwise regression analysis showed that age,primary caregiver's occupation entered the regression equation(P<0.05).Conclusion:Children with precocious puberty have low health-related quality of life during treatment.Medical staff should take targeted measures according to the age of children and different treatment methods.For patients'caregivers,nurses should improve their knowledge of precocious puberty and reduce their negative emotion to improve ICPP patients'quality of life indirectly.

关 键 词：性早熟 儿童 生活质量 

分 类 号：R47[医药卫生—护理学]