新生儿高胆红素血症患儿围生期危险因素分析  

Analysis of Perinatal Risk Factors in Neonates with Hyperbilirubinemia

作　　者：杜英 赵志虹 星晓黎 DU Ying;ZHAO Zhi-hong;XING Xiao-li(Department of Obstetrics,Xining First People's Hospital,Xining,Qinghai Province,810000 China)

机构地区：[1]青海省西宁市第一人民医院产科,青海西宁810000

出　　处：《中外医疗》2020年第33期24-26,共3页China & Foreign Medical Treatment

摘　　要：目的观察分析新生儿高胆红素血症患儿围生期的危险因素。方法方便选取该科室于2017年2月—2019年2月分娩的87例高胆红素血症患儿。采用统计学分析不同性别以及不同胎龄新生儿的胆红素水平,单变量分析高胆红素血症的危险因素,Logistic多元回归分析新生儿高胆红素血症患儿的围生期独立危险因素。结果43例男患儿胆红素水平为(311.2±30.2)μmol/L,44例女患儿胆红素水平为(318.5±27.8)μmol/L,不同性别新生儿的胆红素水平比较,差异无统计学意义(t=1.173,P>0.05);60例足月儿胆红素水平为(286.3±20.8)μmol/L、27例早产儿胆红素水平为(355.9±33.4)μmol/L,早产儿胆红素水平显著高于足月儿,差异有统计学意义(t=11.860,P<0.05);单变量分析高胆红素血症的危险因素有:①早产儿;②新生儿窒息;③胎膜早破等(P<0.05);Logistic多元回归分析新生儿高胆红素血症患儿的围生期独立危险因素有:①胎龄;②催产素;③胎粪排出时间等(OR=0.635、0.524、0.145,P<0.05)。结论新生儿高胆红素血症的发生与早产儿、新生儿窒息等因素密切相关。Objective To observe and analyze the perinatal risk factors of neonatal hyperbilirubinemia.Methods Eighty-seven children with hyperbilirubinemia who were delivered in the department from February 2017 to February 2019 were conveniently selected.The bilirubin levels of neonates of different genders and gestational ages were statistically analyzed,the risk factors of hyperbilirubinemia were analyzed by univariate analysis,and the independent risk factors in perinatal period were analyzed by Logistic multiple regression analysis.Results The bilirubin levels were(311.2±30.2)μmol/L in 43 male children,(318.5±27.8)μmol/L in 44 female children,and there was not statistically significant difference in bilirubin levels among newborns of different sex(t=1.173,P>0.05);in 60 full-term children(286.3±20.8)μmol/L,in 27 preterm infants(355.9±33.4)μmol/L,the difference was statistically significant(t=11.860,P<0.05);the risk factors of hyperbilirubinemia were as follows:1.preterm infants;2.neonatal asphyxia;3.premature rupture of membranes(P<0.05);Logistic multivariate regression analysis of perinatal independent risk factors in children with neonatal hyperbilirubinemia were:1.gestational age;2.oxytocin;3.meconium excretion time,etc(OR=0.635,0.524,0.145,P<0.05).Conclusion The occurrence of neonatal hyperbilirubinemia is closely related to preterm infants and neonatal asphyxia.

关 键 词：新生儿 高胆红素血症 围生期 宫内窘迫 催产素 胎膜早破 

分 类 号：R722.1[医药卫生—儿科]