Biomineralized and chemically synthesized magnetic nanoparticles:A contrast  

作　　者：Tanya NANDA Ankita RATHORE Deepika SHARMA 

机构地区：[1]Present adress:School of Biological and Health Systems Engineering,Ira A.Fulton Schools of Engineering,Arizona State University,Tempe,AZ 85281,USA [2]Present address:Academy of Scientific and Innovative Research(AcSir),CSIR-National Institute of Science Communication and Information Resources(NISCAIR),New Delhi 110067,India [3]Institute of Nano Science and Technology,Habitat Centre,Sector 64,Mohali 160062,India

出　　处：《Frontiers of Materials Science》2020年第4期387-401,共15页材料学前沿（英文版）

基　　金：supported by a grant from the Department of Science and Technology(DST-SERB project,Grant No.ECR/2017000049)。

摘　　要：Magnetic nanoparticles(MNPS)have widely been synthesized through chemical processes for biomedical applications over the past few decades.Recently,a new class of MNPs,known as bacterial magnetosomes,has been isolated from magnetotactic bacteria,a natural source.These magnetosomes are magnetite or greigite nanocrystals which are biomineralized in the bacterial cell and provide magnet-like properties to it.Contrary to MNPs,bacterial magnetosomes are biocompatible,lower in toxicity,and can be easily cleared from the body due to the presence of a phospholipid bilayer around them.They also do not demonstrate aggregation,which makes them highly advantageous.In this review,we have provided an in-depth comparative account of bacterial magnetosomes and chemically synthesized MNPs in terms of their synthesis,properties,and biomedical applications.In addition,we have also provided a contrast on how magnetosomes might have the potential to successfully substitute synthetic MNPs in therapeutic and imaging applications.

关 键 词：bacterial magnetosomes magnetic nanoparticles iron nanoparticles magnetotactic bacteria MAGNETOSOMES 

分 类 号：TB383[一般工业技术—材料科学与工程]