热敏灸、针刺治疗排卵障碍性不孕的效果  

Effect of Heat-Sensitive Moxibustion and Acupuncture on Anovulatory Infertility

作　　者：陈姣洁 黄烨[1] 戴桂艳 CHEN Jiao-jie;HUANG Ye;DAI Gui-yan(Department of Gynecology,Jiangxi University of Traditional Chinese Medicine Affiliated Hospital,Nanchang 330006,China;Department of Gynecology,Taihe Hospital of Chinese Medicine,Taihe 343700,China)

机构地区：[1]江西中医药大学附属医院妇科,南昌330006 [2]泰和县中医院妇科,江西泰和343700

出　　处：《实用临床医学（江西）》2020年第10期35-38,共4页Practical Clinical Medicine

基　　金：江西省卫生计生委中医药科研项目[2016B047]。

摘　　要：目的评价热敏灸、针刺治疗排卵障碍性不孕的效果。方法纳入2017年4月至2019年12月门诊就诊的200例肾虚血瘀型排卵障碍性不孕患者。采用随机数字表法将其分为中医治疗组(热敏灸+针刺+补肾活血中药)、中医对照组[补肾活血中药+人绒毛膜促性腺激素(HCG)],中西医治疗组(热敏灸+针刺+克罗米芬)、中西医对照组(克罗米芬+HCG),每组50例,均进行3个月经周期的治疗,监测卵泡期卵泡发育情况。治疗结束时,两大组平行对照比较治疗组和其对照组的围排卵期子宫内膜厚度、排卵情况,治疗效果及不良反应,并动态随访半年内受孕率。结果治疗后,中医治疗组围排卵期子宫内膜厚度大于中医对照组(P<0.05),排卵率及妊娠率高于中医对照组(70.1%比56.7%;40%比20%,P<0.05)。中西医治疗组和中西医对照组围排卵期子宫内膜厚度比较差异无统计学意义(P>0.05),中西医治疗组排卵率及妊娠率均高于中西医对照组(66.7%比52.0%;36%比16%,P<0.05)。中医治疗组总有效率为88%,高于中医对照组的72%(P<0.05);中西医治疗组总有效率为84%,高于中西医对照组的66%(P<0.05)。结论热敏灸、针刺治疗排卵障碍性不孕可促进卵泡发育,提高排卵率和妊娠率。Objective To explore the effect of heat-sensitive moxibustion and acupuncture on anovulatory infertility.Methods Two hundred patients who visited outpatient clinics from April 2017 to December 2019 for anovulatory infertility due to kidney deficiency and blood stasis were selected in this study.These patients were randomly divided into 4 groups:traditional Chinese medicine treatment group(heat-sensitive moxibustion+acupuncture+tonifying kidney and promoting blood circulation),traditional Chinese medicine control group(tonifying kidney and promoting blood circulation+human chorionic gonadotropin),integrated Chinese and Western medicine treatment group(heat-sensitive moxibustion+acupuncture+enclomiphene),and integrated Chinese medicine control group(enclomiphene+human chorionic gonadotropin),with 50 patients in each group.All patients were treated for 3 menstrual cycles and follicular development during the follicular phase was monitored.At the end of treatment,the endometrial thickness,ovulation,therapeutic outcomes and adverse reactions were observed,and the pregnancy rate was followed up within half a year.Results After treatment,compared with the integrated Chinese medicine control group,the traditional Chinese medicine treatment significantly increased endometrial thickness,ovulation rate(70.1%vs 56.7%)and pregnancy rate(40%vs 20%)(P<0.05).There was no significant difference in endometrial thickness between the integrated Chinese and Western medicine control group and the integrated Chinese and Western medicine treatment group.However,the ovulation rate,pregnancy rate and overall response rate in the integrated Chinese and Western medicine treatment group were higher than those in the integrated Chinese and Western medicine control group(66.7%vs 52.0%,36%vs 16%and 84%vs 66%,respectively;P<0.05).In addition,the overall response rate in the traditional Chinese medicine treatment group was higher than that in the traditional Chinese medicine control group(88%vs 72%,P<0.05).Conclusion Heat-sensitive moxibustion an

关 键 词：排卵障碍不孕 热敏灸 针刺 中医治疗 子宫内膜厚度 排卵率 妊娠率 

分 类 号：R711.6[医药卫生—妇产科学]