补肾填精、祛瘀化痰法治疗血管性痴呆的临床疗效观察  

Clinical Observation on Treatment of Vascular Dementia by Bushen Tianjingand Quyu Huatan

作　　者：阮娟娟 魏霞 Ruan Juanjuan;Wei Xia(Department of Neurology,Zhumadian Hospital of Traditional Chinese Medicine,Zhumadian 463000)

机构地区：[1]驻马店市中医院神经内科,驻马店463000

出　　处：《数理医药学杂志》2021年第1期74-76,共3页Journal of Mathematical Medicine

基　　金：2015年度河南省重点中医学科,编号2015ZY03030,补肾填精、祛瘀化痰法治疗血管性痴呆的临床疗效观察,课题负责人:魏霞。

摘　　要：目的:观察补肾填精、祛瘀化痰法治疗血管性痴呆(Vascular dementia,VD)的临床疗效及应用价值。方法:选取某院神经内科2017年12月~2019年12月收治的70例VD患者,根据随机数字表法平均分为中医组和对照组各35例,对照组给予常规药物治疗,中医组在对照组基础上给予自拟补肾祛瘀化痰中药疗法,均治疗4周。评估两组治疗疗效,并记录治疗前后各项临床指标的变化,如长谷川痴呆量表(HDS)评分、简易精神状态量表(MMSE)评分、日常生活能力量表(ADL)评分及不良反应发生情况。结果:中医组总有效率(91.43%)高于对照组(71.43%),差异具有统计学意义(P<0.05);治疗前两组HDS评分、MMSE评分及ADL评分比较无明显差异(P>0.05),治疗后各项指标均明显改善(P<0.05),且中医组优于对照组(P<0.05);治疗期间两组均出现恶心呕吐、头晕乏力、呼吸困难等不良反应,但两组不良反应发生率比较无统计学差异(P>0.05)。结论:补肾填精、祛瘀化痰中医法治疗VD患者效果显著,能显著改善临床病症及精神状态,提高生活质量,有助于康复。Objective:To observe the clinical efficacy and application value of Bushen Tianjing,Quyu Huatan in the treatment of vascular dementia(VD).Methods:70 cases of VD patients in a hospital from December 2017 to December 2019 were selected and evenly divided into TCM group(n=35)and control group(n=35)according to random number table method.The control group was given conventional drug treatment,and the TCM group was given self-made Chinese medicine therapy of Bushen Tianjing and Quyu Huatan on the basis of the control group,all of which were treated for 4 weeks.The therapeutic effects of the two groups were evaluated,and the changes of clinical indexes before and after treatment were recorded,such as Hasegawa Dementia Scale(HDS),Mini Mental State Scale(MMSE),activities of daily living(ADL)score and adverse reactions.Results:The total effective rate of TCM group(91.43%)was higher than that of control group(71.43%),the difference was statistically significant(P<0.05).Before treatment,the HDS score,MMSE score and ADL score of the two groups were no significant difference(P>0.05),after treatment,all indexes were significantly improved(P<0.05),and the TCM group was better than the control group(P<0.05).During the treatment,both groups had nausea and vomiting,and there was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion:Traditional Chinese medicine treatment of Bushen Tianjing and Quyu Huatan in the treatment of VD patients has significant effect,which can significantly improve the clinical symptoms and mental state,improve the quality of life,and is conducive to rehabilitation.

关 键 词：补肾填精 祛瘀化痰 血管性痴呆 精神状态 

分 类 号：R277.7[医药卫生—中医学]