162例CRE感染的分布特点及降低细菌感染措施评价研究  

The distribution characteristics of 162 cases of CRE infection and evaluation of measures to reduce bacterial infection

作　　者：张雁[1] 梁家花 张峰[3] ZHANG Yan;LIANG Jiahua;ZHANG Feng(Department of Inspection,Mental Health Center,Rizhao,Shangdong,China,267800;Department of Laboratory Medicine,Juxian People's Hospital,Rizhao,Shangdong,China,267800;Department of Clini-cal Laboratory,Rizhao City Hospital of Traditional Chinese Medicine,Rizhao,Shandong,China,267800)

机构地区：[1]日照市精神卫生中心检验科,山东日照276800 [2]莒县人民医院检验科,山东日照276800 [3]日照市中医医院检验科,山东日照276800

出　　处：《分子诊断与治疗杂志》2020年第12期1670-1673,共4页Journal of Molecular Diagnostics and Therapy

摘　　要：目的研究全院碳青霉烯类耐药肠杆菌科细菌(CRE)感染的分布特点及降低细菌感染措施评价研究。方法选取2018年1月至2019年12月于本院住院并接受抗菌药物治疗患者162例,分析患者一般资料,检测结果和干预结果,以是否进行MDT干预分为观察组(n=80)和对照组(n=82)。观察分析两组CRE科室分布情况、细菌标本来源、细菌种类分布情况,比较两组送检率、医院感染率、CRE感染发现率和检出率及各项防控措施落实依从率。结果两组CRE感染科室分布均以呼吸内科为主,检测标本来源均以痰液为主,病原菌均以肺炎克雷伯菌为主,观察组送检率(100.00%)显著高于对照组(95.12%),差异具有统计学意义(P<0.05)。观察组医院感染比例(10.02%)低于对照组(10.51%),观察组CRE感染发现率(8.77%)低于对照组(10.00%),观察组CRE感染检出率(33.05%)低于对照组(41.12),差异无统计学意义(P>0.05),观察组的各项防控措施实施依从率显著优于对照组,差异具有统计学意义(P<0.05)。结论全院碳青霉烯类耐药肠杆菌科细菌感染主要分布在呼吸内科,采用MDT对细菌感染防控进行干预,可以提高患者标本送检率和各项防控措施实施的依从率,降低医院感染率和CRE感染率。Objective To explore the distribution of Carbapenem⁃resistant Enterobacterales(CRE)in our hospital and to evaluate the application effect of the measures to reduce these bacterial infection.Method We retrospectively analyzed 162 cases who had Carbapenem⁃resistant Enterobacterale infection from January,2018 to December,2019.The MDT intervention was divided into the control group(n=82)and the ob⁃servation group(n=80).To observe and analyze the distribution of CRE departments,the origin of bacterial specimens and the distribution of bacterial species in the two groups,and to compare the examination rate,noso⁃comial infection rate,detection rate and detection rate of CRE infection and compliance rate of various preven⁃tion and control measures.Results The distribution of CRE infection departments in both groups was mainly respiratory medicine,sputum was the main source,Klebsiella pneumoniae was the main pathogen,the rate of examination in the observation group(100.00%)was significantly higher than that in the control group(95.12%),the difference was statistically significant(P<0.05),hospital infection rate(10.02%)in the observa⁃tion group was significantly lower than that in the control group(10.51%),CRE infection rate(8.77%)in the ob⁃servation group was lower than that in the control group(10.00%).The detection rate of CRE infection in the ob⁃servation group(8.77%)was lower than that in the control group(10.00%),and the detection rate of CRE infec⁃tion in the observation group(33.05%)was lower than that in the control group(41.12),but the difference was not statistically significant(P>0.05).The compliance rate of various prevention and control measures in the obser⁃vation group was significantly better than that in the control group,and the difference was statistically significant(P<0.05).Conclusion The carbapenem⁃resistant Enterobacteriaceae bacterial infections in the whole hospital are mainly distributed in the Department of Respiratory Medicine.The use of MDT to intervene in the prevention

关 键 词：碳青霉烯类 耐药 肠杆菌科细菌 多学科协作模式 

分 类 号：R446.5[医药卫生—诊断学]