广东省HIV感染孕产妇及所生婴儿特征分析  

Analysis on the characteristics of HIV-infected maternal and their babies in Guangdong Province

作　　者：汤柳英[1] 周映娜 王雄虎[1] 高爽[1] 夏建红[1] TANG Liu-ying;ZHOU Ying-na;WANG Xiong-hu;GAO Shuang;XIA Jian-hong(Guangdong Women and Children Hospital,Guangzhou 511442,China;Huangpu Health and Family Planning Service Center,Zhongshan 528429,China)

机构地区：[1]广东省妇幼保健院,广州511442 [2]黄圃镇卫生与计划生育服务中心,中山528429

出　　处：《中华疾病控制杂志》2020年第12期1470-1474,共5页Chinese Journal of Disease Control & Prevention

基　　金：国家科技重大专项(2015ZX10001001);广东省医学科研基金(C2019067)。

摘　　要：目的了解广东省人类免疫缺陷病毒(human immunodeficiency virus, HIV)感染孕产妇及所生婴儿特征,为预防HIV母婴传播(mother-to-child transmission, MTCT)综合干预服务提供参考依据。方法利用国家预防MTCT信息管理系统监测数据,收集2006—2017年广东省HIV感染孕产妇及所生婴儿一般资料和接受预防HIV MTCT服务相关资料,比较HIV感染再生育孕产妇及所生婴儿与初次生育孕产妇及所生婴儿的差异。结果 2 094例HIV感染孕产妇数中,再生育孕产妇占比61.70%,平均年龄为(30.2±5.3)岁,文化程度以初中/高中为主(54.18%);与初次生育孕产妇相比,再生育孕产妇HIV初检孕周较晚[28.0(14.0, 39.0)vs 17.0(12.0, 28.3),周],产时/产后确诊占比高(41.18%vs 10.10%),性伴HIV感染状态普遍不详(54.57%vs 41.52%),接受抗病毒治疗比例不高(62.77%vs 87.41%),治疗开始时期晚(产时/产后开始治疗占比19.24%vs 6.28%),所生婴儿接受预防性治疗的比例不高(82.35%vs 91.90%),混合喂养占比较稍高(6.94%vs 3.42%)。结论广东省HIV感染孕产妇预防HIV MTCT服务利用度不高,加强HIV感染孕产妇的健康意识,提升医务人员对HIV感染孕产妇及所生婴儿的关注,特别是再生育孕产妇,有助于推进广东省预防HIV MTCT项目工作。Objective To investigate the characteristics of HIV-infected maternal and their babies in Guangdong Province, and to improve services on prevention of HIV mother-to-child transmission(MTCT). Methods Exporting monitoring data from national information management system for prevention MTCT, the general information and the relevant data about HIV prevention MTCT services from HIV-infected pregnant women and their babies in Guangdong Province from 2006 to 2017 were collected to compare the differences between different parities maternal. Results Among the 2 094 HIV-infected pregnant women, 61.70% were re-pregnant women, whose average age were(30.2±5.3) years old, the education level was mainly in junior high/senior high school(54.18%). Compared with the first-time pregnant maternal, re-pregnant maternal were tend to screening on later gestational age [28.0(14.0, 39.0) vs 21.0(13.0, 38.0), weeks], with a high proportion of confirmed time during intrapartum/postpartum(41.18% vs 10.10%), HIV infection status of sexual partner was unknown(54.57% vs 41.52%), generally, the proportion of anti-viral treatment was not high(62.77% vs 87.41%), treatment begins late(intrapartum/postpartum started treatment accounted for 19.24% vs 6.28%). The preventive treatment rate of their infants were not high(82.35% vs 91.90%), while mixed feeding rate was higher(6.94% vs 3.42%). Conclusions The utilization of HIV MTCT in prevention of HIV-infected maternal in Guangdong was not high. Strengthening the health awareness of HIV-infected maternal, and enhancing the attention of medical staff to HIV-infected maternal and their babies, espesially among those re-pregnant women, are helpful to promote the work of prevention of HIV MTCT project in Guangdong Province.

关 键 词：人类免疫缺陷病毒 孕产妇 母婴传播 

分 类 号：R181[医药卫生—流行病学]