湖州市2013—2018年人感染H7N9禽流感病例流行病学特征和外环境监测分析  

Epidemiological characteristics of human infection with avian influenza A(H7N9)virus and detection in external environment in Huzhou,2013-2018

作　　者：闻栋[1] 刘光涛[1] 纪蕾[2] 孙秀秀 张驰宇[3] 韩建康[4] Wen Dong;Liu Guangtao;Ji Lei;Sun Xiuxiu;Zhang Chiyu;Han Jiankang(Department of Infectious Disease,the Center for Disease Control and Prevention of Huzhou,Huzhou 313000,Zhejiang,China;Department of Microbiological Laboratory,the Center for Disease Control and Prevention of Huzhou,Huzhou 313000,Zhejiang,China;Key Laboratory of Molecular Virology&Immunology,Institut Pasteur of Shanghai,Chinese Academy of Sciences,Shanghai 200031,China;Department of Administration Office,the Center for Disease Control and Prevention of Huzhou,Huzhou 313000,Zhejiang,China)

机构地区：[1]湖州市疾病预防控制中心传染病预防控制科,浙江湖州313000 [2]湖州市疾病预防控制中心微生物检验科,浙江湖州313000 [3]中国科学院,上海巴斯德研究所分子病毒学与免疫学重点实验室,200031 [4]湖州市疾病预防控制中心办公室,浙江湖州313000

出　　处：《国际流行病学传染病学杂志》2020年第6期514-517,共4页International Journal of Epidemiology and Infectious Disease

基　　金：浙江省自然科学基金(LY16H260001);湖州市科学技术局项目(2016GY29)。

摘　　要：目的了解湖州市人感染H7N9禽流感病例的流行病学特征及外环境样本检测情况。方法收集2013—2018年现住址为湖州市的人感染H7N9禽流感确诊病例的流行病学信息,同时采集暴露可疑环境样本进行病原学检测。运用Spearman相关分析法分析发病数与环境阳性检出率的关系。结果2013—2018年湖州市确诊的人感染H7N9禽流感病例39例,死亡9例,病死率为23.08%。男性多于女性,病例主要60岁以上的老年群体和农民。病例溯源样本阳性检出率为8.47%(30/345),农贸市场活禽交易场所的阳性检出率为25.00%(127/508),发病数与样本、场所检出阳性率的Spearman相关系数分别为0.379和0.392。结论中老年男性及农民是人感染H7N9禽流感的高发群体,活禽暴露是发病的高危因素。Objective To understand the epidemiological characteristics of human infection with avian influenza A(H7N9)virus in Huzhou City and monitoring results of H7N9 virus in external environment.Methods The epidemiological information of confirmed cases with H7N9 virus infection living in Huzhou City from 2013 to 2018 was collected,and the samples exposed to the environment were collected for pathogenic detection.Spearman correlation analysis was used to analyze the relationship between the incidence of H7N9 virus infection and positive detection rate in the environment.Results From 2013 to 2018,39 cases with H7N9 virus infection were confirmed in Huzhou,and 9 cases died with the fatality rate of 23.08%.Male cases were more than female ones,and the majority was in the elderly population over 60 years old and farmers.The positive rates of household samples from the patients and samples from live poultry trading places in agricultural markets were 8.47%(30/345)and 25.00%(127/508),respectively.Spearman correlation coefficient between the incidence of H7N9 virus infection and positive detection rates of household and market samples were 0.379 and 0.392,respectively.Conclusions The elderly male population and farmers are susceptible groups for human infection with H7N9 virus.Exposure history of live poultry is the high risk factor of infection.

关 键 词：流感病毒A型 H7N9 流行病学 活禽 暴露 

分 类 号：R511.7[医药卫生—内科学] R181.3[医药卫生—临床医学]