老年女性腰椎骨密度的独立影响因素  

Independent influencing factors of lumbar spine bone mineral density in elderly women

作　　者：倪霞萍[1] 钟瑶 胡琳[1] 来芹美[1] 边平达[1] Ni Xiaping;Zhong Yao;Hu Lin;Lai Qinmei;Bian Pingda(Department of Geriatrics,Zhejiang Provincial People′s Hospital & People′s Hospital of Hangzhou Medical College,Hangzhou 310024,China)

机构地区：[1]浙江省人民医院/杭州医学院附属人民医院望江山院区老年医学科,杭州310024

出　　处：《中国临床保健杂志》2020年第6期797-800,共4页Chinese Journal of Clinical Healthcare

基　　金：浙江省医药卫生平台重点资助计划项目(2016ZDA002)。

摘　　要：目的通过筛选老年女性腰椎骨密度(LSBMD)的独立影响因素,来寻找可能提高老年女性LSBMD的方法。方法对344例老年女性的一般状况进行调查,并检测其LSBMD(双能X线吸收检测法)、骨代谢标志物、血生化等指标,运用多元线性回归分析方法筛选老年女性LSBMD的独立影响因素。结果多元线性回归分析显示:老年女性LSBMD的独立影响因素有体质指数(β=0.015,P<0.01)、I型胶原羧基末端肽交联(β=-0.159,P<0.01)、慢性阻塞性肺疾病(COPD)(β=-0.104,P<0.01)、尿酸(β=0.369,P<0.01)和低密度脂蛋白胆固醇(β=-0.022,P<0.05)。结论维持合理的体质指数、尿酸、低密度脂蛋白胆固醇水平,积极防治COPD,可能有助于提高老年女性LSBMD。Objective To find out the independent factors of lumbar spine bone mineral density(LSBMD)in elderly women.Methods A cross-sectional survey was conducted which included 344 elderly women.The markers of bone metabolism,blood biochemistry,LSBMD(dual energy X-ray absorption test)were detected.Multiple linear regression analysis was used to screen the independent influencing factors of LSBMD in elderly women.Results Multiple linear regression analysis showed that body mass index(β=0.015,P<0.01),type I collagen carboxy-terminal peptide cross-linking(β=-0.159,P<0.01),chronic obstructive pulmonary disease(COPD)(β=-0.104,P<0.01),uric acid(β=0.369,P<0.01)and low-density lipoprotein cholesterol(β=-0.022,P<0.05)were independent influencing factors for LSBMD in elderly women.Conclusion Maintaining reasonable body mass index,uric acid,low-density lipoprotein cholesterol levels,and actively preventing and treating COPD may be important methods to improve LSBMD in elderly women.

关 键 词：腰椎 骨密度 危险因素 女性 老年人 

分 类 号：R58[医药卫生—内分泌]