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作 者:李铁 徐文东 Li Tie;Xu Wendong(Department of Hand Surgery,Huashan Hospital,Fudan University,Shanghai 200040,China;Limb Function Reconstruction Center,Jing'an District Central Hospital,Fudan University,Shanghai 200040,China;The National Clinical Research Center for Aging and Medicine,Shanghai 200044,China;Engineering Research Center of Artificial Intelligence Medical Auxiliary Equipments,Shanghai 200030,China.)
机构地区:[1]复旦大学附属华山医院手外科,上海200040 [2]复旦大学附属静安区中心医院肢体功能重建中心,上海200040 [3]国家老年疾病临床医学研究中心,上海200044 [4]上海市人工智能医疗辅助器具工程研究中心,上海200030
出 处:《生物医学转化》2020年第1期86-89,95,共5页Biomedical transformation
基 金:国家自然科学基金(创新研究群体项目:82021002,重点项目:81830063,青年项目:81801363);上海市科委科研计划项目(19MC1910500,18411950100);上海市卫生和计划生育委员会科研课题资助项目(20184Y0111,201640176);上海市“医苑新星”青年医学人才培养资助计划。
摘 要:肢体瘫痪是人类致残的最主要原因,仅脑卒中等造成的偏瘫在我国就达两千余万患者,长期“无医可治”。中国原创的左右颈七神经交叉移位,将瘫痪上肢神经换接到同侧健康大脑,不仅偏瘫肢体功能显著恢复,更进一步更新发展了传统脑科学理论。然而对于脊髓损伤后肢体瘫痪或严重肢体残缺患者来说仅依靠医学方法尚不能有效治疗。近年来,围绕传统脑电技术发展而来的脑机接口等新兴技术衍生出的交叉学科逐渐兴起,拥有能够解决医学遗留难题的潜能,在国内外掀起一番热潮。作为国家战略需求,研究者应当抓住机会,加大力度支持跨领域、多学科融合,共同研发肢体功能重建新方案,实现新兴科技与中国原创技术融合的再次突破。Limb paralysis is the main cause of human disability.Hemiplegia caused by stroke alone has affected more than 20 million patients in China,and there is currently no cure for this disease.We created the original contralateral C7 to C7 cross nerve transfer surgery that swapped the link of the brachial nerve of the paralyzed side to the ipsilateral healthy brain.Not only did hemiplegic limb function recover significantly,it also broke the traditional neuroscience theory.However,for patients with limb paralysis or severe limb disability after spinal cord injury,the practicality of traditional medical methods is still facing the doubt of effectiveness.In recent years,interdisciplinary cooperation derived from emerging technologies such as brain-computer interfaces based on the development of traditional EEG technology have gradually risen.They have the potential to solve the problems left over from traditional medicine and have taken a great upsurge at home and abroad.As a national strategic demand,we should seize this opportunity to increase our efforts to support cross-field and multi-disciplinary integration to jointly develop new solutions for limb function reconstruction,and achieve another breakthrough in the integration of emerging technologies and Chinese original technologies.
关 键 词:脑机接口 肢体功能重建 左右颈七神经交叉移位术 多学科融合
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