Banff移植病理学诊断标准的起源、发展及对器官移植的推动作用  

The origin and development of Banff classification on allograft pathology and its effects in promoting organ transplantation

作　　者：郭晖[1] 陈刚[1] Guo Hui;Chen Gang(Institute of Organ Transplantation,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Key Laboratory of Organ Transplantation of Ministry of Education,Key Laboratory of Organ Transplantation of National Health Commission of China,Key Laboratory of Organ Transplantation of Chinese Academy of Medical Sciences,Wuhan 430030,China)

机构地区：[1]华中科技大学同济医学院附属同济医院器官移植研究所,器官移植教育部重点实验室,国家卫生健康委员会,器官移植重点实验室,中国医学科学院器官移植重点实验室,武汉430030

出　　处：《器官移植》2021年第1期15-22,共8页Organ Transplantation

基　　金：国家自然科学基金(81771719);中国医学科学院中央级公益性科研院所基本科研业务费专项资金(2019PT320014)。

摘　　要：Banff移植病理学会议(Banff会议)的召开及Banff移植病理学诊断标准(Banff标准)的建立是国际移植病理学发展的里程碑。目前世界各器官移植中心均常规依据Banff标准进行移植肾的活组织检查(活检)病理学诊断。随后移植肾Banff标准的研讨和更新模式很快扩展至移植心脏、移植肺、移植肝、移植胰腺和移植小肠等各类移植器官。Banff会议不仅成为包含各类移植器官病理学研讨的专题会议,而且也为各类移植器官的活检逐步制定了统一的诊断标准,更好地促进了器官移植术后并发症的明确诊断和治疗。本文总结了国际移植病理学研究的历史、Banff会议及Banff标准对器官移植的推动作用,旨在为临床器官移植的顺利开展提供参考。The Banff conference on allograft pathology(Banff conference)and the establishment of Banff classification on allograft pathology(Banff classification)are milestones in the development of international allograft pathology.At present,all organ transplantation centers around the world routinely perform pathological diagnosis by biopsy of the transplant kidney according to Banff classification.Subsequently,the consensus process and update mode of Banff classification for transplant kidney was quickly extended to transplant heart,lung,liver,pancreas,and small intestine,etc.The Banff conference has not only become a thematic meeting that includes the pathology study and discussion of various transplant organs,but also gradually developed unified diagnostic standard for the biopsy of each transplant organ,which better promoted the accurate diagnosis and treatment of complications after organ transplantation.This article summarized the history of international allograft pathology research,the Banff conference and Banff classification in promoting organ transplantation,which aimed to provide a reference for the smooth development of clinical organ transplantation.

关 键 词：移植病理学 器官移植 Banff会议 活组织检查 病理学诊断标准 抗体介导的排斥反应 T细胞介导性排斥反应 C4D 

分 类 号：R617[医药卫生—外科学] R36[医药卫生—临床医学]