1,8-桉叶素药理作用及其机制研究进展  

Research progress on pharmacological activities and mechanism of 1,8-cineole

作　　者：尹晓燕 王燕燕[2] YIN Xiaoyan;WANG Yanyan(Medical College of Three Gorges University,Yichang 443002,China;Yichang Central People's Hospital,Yichang 443002,China)

机构地区：[1]三峡大学医学院,宜昌443003 [2]宜昌市中心人民医院,宜昌443003

出　　处：《生命的化学》2020年第11期2026-2034,共9页Chemistry of Life

基　　金：国家自然科学基金项目(31570361)。

摘　　要：1,8-桉叶素是一种环状单萜类化合物,为桉油的主要成分,含量高达84%,主要存在于桃金娘科植物蓝桉和樟科植物樟树中。1,8-桉叶素具有促进透皮吸收、抗炎、抗氧化、抗微生物、抗肿瘤等药理作用,对呼吸系统、神经系统、循环系统和消化系统均有一定的保护作用,且安全性良好。本文就其药理活性及作用机制的研究现状进行综述,以期为1,8-桉叶素的深入研究和开发利用提供理论参考。1,8-cineole,also known as eucalyptol,is a bicyclic monoterpenoid,and has been isolated from essential oils prepared from Eucalyptus globulus Labill.and Cin-namomum camphora(L.)Presl.It displays extensive biological properties including anti-inflammation,anti-oxidative stress,anti-tumor,enhancement of transdermal penetration and inhibition of microbial growth.It also has certain protective effects on our respiratory,nervous,circulatory and digestive systems.This paper mainly summarizes the latest development of the pharmacological activities and mechanism of 1,8-cineole,which could lay a foundation for the further studies of this molecule.

关 键 词：1 8-桉叶素 单萜 药理活性 作用机制 

分 类 号：R285[医药卫生—中药学]