剖宫产麻醉患者应用托烷司琼联合咪达唑仑预防术后呕吐的效果分析  

Analysis of effects of tropisetron and midazolam in preventing postoperative vomiting in patients with cesareansection anesthesia

作　　者：毕路甲[1] 闫军杰[1] BI Lu-jia;YAN Jun-jie(Department of Anesthesiology,The Second Affiliated Hospital of Luohe Technical College,Luohe 462300,Henan Province,China)

机构地区：[1]漯河医学高等专科学校第二附属医院麻醉科,河南漯河462300

出　　处：《罕少疾病杂志》2021年第1期49-50,共2页Journal of Rare and Uncommon Diseases

摘　　要：目的研究剖宫产麻醉患者应用托烷司琼联合咪达唑仑预防术后呕吐的效果,并评价其安全性。方法将本院2018年3月至2019年2月收治的144例剖宫产麻醉患者使用随机数字表法分为观察组和对照组,每组72例。对照组给予托烷司琼治疗,观察组给予托烷司琼+咪达唑仑联合治疗,观察两组术后呕吐发生情况和不良反应发生情况。结果观察组呕吐总发生率为18.06%,低于对照组(36.11%,P<0.05);观察组呕吐程度Ⅰ-Ⅲ级例数均少于对照组(P<0.05);在不良反应发生率方面,观察组为16.67%,高于对照组(9.72%),但差异无统计学意义(P>0.05)。结论剖宫产麻醉患者应用托烷司琼联合咪达唑仑预防术后呕吐的效果很好,用药安全。Objective To study the effects of tropisetron and midazolam in preventing postoperative vomiting in patients with cesarean section anesthesia and evaluating its safety.Methods A total of 144 patients with cesarean section anesthesia admitted to the hospital from March 2018 to February 2019 were randomly divided into observation and control groups according to the 72 cases in each group.the control group was treated with tropisetron,and the observation group was treated with tropisetron+midazolam.The occurrence of postoperative vomiting and the occurrence of adverse reactions were observed in the two groups.Results The total incidence rate of vomiting in the observation group was lower than that in the control group(18.06%vs 36.11%)(P<0.05).The number of cases with I-III degree of vomiting in the observation group was lower than that in the control group(P<0.05).The incidence rate of adverse reactions in the observation group was higher than that in the control group(16.67%vs 9.72%)(P>0.05).Conclusion Tropisetron combined with midazolam for patients with cesarean section anesthesia is effective in preventing postoperative vomiting and is safe to use.

关 键 词：剖宫产 托烷司琼 咪达唑仑 术后呕吐 效果分析 

分 类 号：R719.8[医药卫生—妇产科学] R982[医药卫生—临床医学]