天山假狼毒的化学成分研究(Ⅲ)  

Chemical constituents of Stelleropsis tianschanica(Ⅲ)

作　　者：姚彩虹 魏鸿雁 马晓玲 阿勒腾图娅 陈刚 石磊岭 YAO Cai-hong;WEI Hong-yan;MA Xiao-ling;ALE Teng-tuya;CHEN Gang;SHI Lei-ling(School of Life Science and Technology,Xinjiang University,Urumqi 830046,China;Xinjiang Institute of Chinese and Ethnic Medicine,Urumqi 830002,China)

机构地区：[1]新疆大学生命科学与技术学院,新疆乌鲁木齐830046 [2]新疆维吾尔自治区中药民族药研究所,新疆乌鲁木齐830002

出　　处：《中草药》2020年第23期5929-5933,共5页Chinese Traditional and Herbal Drugs

基　　金：新疆维吾尔自治区自然科学基金面上项目(2018D01A37)。

摘　　要：目的研究天山假狼毒Stelleropsis tianschanica的化学成分。方法运用柱色谱方法对天山假狼毒95%甲醇提取物进行分离纯化,结合波谱技术与理化常数鉴定结构。结果从天山假狼毒中分离得到了12个化合物,包括黄酮类7个、木脂素类2个、其他类3个,分别鉴定为荛花醇A(1)、芫花醇乙(2)、viburnolide A(3)、genkwanol B(4)、芫花酚C(5)、瑞香酚(6)、邻苯二甲酸二丙酯(7)、邻苯二甲酸二异丁酯(8)、1,3,5-三羟基-2-甲氧基苯(9)、松柏苷(10)、紫丁香酚苷(11)、金合欢素(12)。结论化合物1~2、5~6、9~12为均为首次从该属植物中分离得到。Objective To study the chemical constituents from Stelleropsis tianschanica. Methods The constituents were isolated from S. tianschanica and purified by column chromatography, and the structures were identified by spectral analysis and chemical methods. Results A total of 12 compounds were isolated from S. tianschanica, including seven flavonoids compounds, two lignans compounds, and the other three compounds, and the structures were identified as wikstrol A(1), wikstrol B(2), viburnolide A(3), genkwanol B(4), genkwanol C(5), stelleranol(6), dipropyl phthalate(7), diisobutyl phthalate(8), 1,3,5-triol-2-methoxybenzene(9), coniferin(10), syringin(11), and acacetin(12). Conclusion Compounds 1—2, 5—6, 9—12 are isolated from the genus Stelleropsis for the first time.

关 键 词：天山假狼毒 黄酮类 木脂素类 金合欢素 瑞香酚 荛花醇A 芫花醇乙 

分 类 号：R284.1[医药卫生—中药学]