Acoustophoretic Motion of Erythrocyte-mimicking Hemoglobin Micromotors  

作　　者：Changyong Gao Zhihua Lin Chang Zhou Daolin Wang Qiang He 

机构地区：[1]Key Laboratory of Microsystems and Microstructures Manufacturing(Minitry of Education),Harbin nstitute of Technology,92 West Doazhi treet,Harbin,Heilongjiang 150001,China

出　　处：《Chinese Journal of Chemistry》2020年第12期1589-1594,共6页中国化学（英文版）

基　　金：This work was financially supported by the National NaturalScience Foundatien ef China(Ne.21902037);National Post-doctoral Program for Innovative Talents(BX201700065).

摘　　要：of main observation and conclusion Biocompatible micromotors have received increasing attention,due to their powerful motion,diverse functionalities and autonomous navigation in the field of biomedical applications.Herein,we report an acoustically-propelled,magnetic-guided,erythrocyte-mimicking hemoglobin micromotor with oxygen-carrying capability.These hemoglobin micromotors were fabricated by encapsulating magnetic nanoparticles in hybrid hemoglobin/calcium carbonate microparticles,followed by covalently layer-by-layer assembly of hemoglobin multilayers.The asymmetric distribution of magnetic nanoparticles enables these micromotors to move rapidly under the propulsion of an acoustic field.The velocity of acoustophoretic motion of hemoglobin micromotors increases with the increase of input voltage of acoustic field,up to 58.2 pirn s^-1 at 10 V.The hemoglobin micromotors are directionally navigated by applying an external magnetic field,and also could pass through microchannels toward the targeted region.Moreover,such hemoglobin micromotors show effective oxygen loading and releasing capability,holding considerable promise as a new platform for oxygen delivery applications.

关 键 词：field. APPLYING AUTONOMOUS 

分 类 号：O64[理学—物理化学]