The anti-hypertensive effect of time acupuncture on the patients with primary hypertension  

辰时针刺对原发性高血压患者的降压效应

作　　者：Yan-jun WANG Xin ZHAO Xiang-dong LAN Shui-qing XU Li-hua ZHANG 王艳君;赵鑫;兰向东;许水清;张丽华(河北中医学院附属医院,石家庄050011;河北省中医院,石家庄050011;河北省沧州中西医结合医院,沧州061000)

机构地区：[1]Affiliated Hospital of Hebei University of Traditional Chinese Medicine,Shijiazhuang 050011,China [2]Heibei Provincial Chinese Medicine Hospital,Shijiazhuang 050011,China [3]Cangzhou Integrated Traditional Chinese and Western Medicine Hospital,Cangzhou 061000,Hebei Province,China

出　　处：《World Journal of Acupuncture-Moxibustion》2020年第4期272-276,共5页世界针灸杂志（英文版）

基　　金：supported by National key R&D Program:No.2018YFC1707803;Subject of Hebei Provincial Department of Finance:No.361025;Project of Hebei Provincial Administration of Traditional Chinese Medicine:No.2017054。

摘　　要：Objective:To observe the anti-hypertensive effect of time acupuncture on primary hypertension so as to provide the therapeutic regimen for the treatment of primary hypertension.Methods:A total of 120 patients with primary hypertension were randomized into a western medication group and an acupuncture-medication group,60 cases in each one.In the western medication group,levoamlodipine maleate tablets were prescribed for oral administration.In the acupuncture-medication group,on the base of the treatment as the western medication group,time acupuncture was combined in the period of a day from 7:00 a.m.to 9:00 a.m.The duration of treatment was 4 weeks in the two groups.Before and after treatment,blood pressure,serum endothelin(ET)and nitrious oxide(NO)were measured successively and the clinical therapeutic effect was evaluated.Results:(1)Blood pressure:the systolic and diastolic pressure after treatment were all lower than that before treatment in the two groups,indicating statistical differences(all P<0.05),After treatment,the systolic and diastolic pressure in the acupuncture-medication group were lower than that of the western medication group,indicating significant differences(both P<0.05).(2)ET and NO:after treatment,ET in the acupuncture-medication group was lower than the western medication group and NO was higher than the western medication group,indicating statistical differences(both P<0.05).(3)Clinical therapeutic effect:the total effective effect of anti-hypertension was 89%in the acupuncture-medication group,higher than 63%in the western medication group,indicating statistical difference(P<0.05).Conclusion:The combined treatment of western medication and time acupuncture(7:00 am to 9:00 am)achieves better effect on primary hypertension as compared with simple western medication and its anti-hypertensive effect is probably related to the decrease of ET and the increase of NO.

关 键 词：ACUPUNCTURE Primary hypertension Anti-hypertensive effect Acupuncture combines with medication Endothelin(ET) Nitrious oxide(NO) 

分 类 号：R246.1[医药卫生—针灸推拿学]