纳米酶与病毒检测  

Nanozymes and Virus Detection

作　　者：刘键[1] 刘昕[2] LIU Jian;LIU Xin(Institute of Health Quarantine,Chinese Academy of Inspection and Quarantine,Beijing 100176,China;Faculty of Environment and Life,Beijing University of Technology,Beijing 100124,China)

机构地区：[1]中国检验检疫科学研究院卫生检验与检疫研究所,北京100176 [2]北京工业大学环境与生命学部,北京100124

出　　处：《北京工业大学学报》2021年第1期93-102,共10页Journal of Beijing University of Technology

基　　金：中国检验检疫科学研究院基本科研业务费专项资金资助项目(2016JK013)。

摘　　要：综述了纳米酶的发展及其在病毒检测中的应用,介绍当前纳米酶研究进展,以期推动纳米酶在医学诊断治疗等领域的广泛应用.通过对比当前常用的检测方法,总结了部分具有代表性的纳米酶检测方法,归纳基于纳米酶特性研发出的检测新技术、新方法及其思路与效果,分析纳米酶面临的挑战.与天然酶相比,纳米酶拥有优越的特性,不仅在病毒检测领域,而且在其他生物医学、环境保护、疾病治疗等各领域发挥越来越重要的作用.随着人们对纳米酶性质和催化机理的深入研究,必将设计出更多功能化的纳米酶,发展出新的快速高效的检测技术.This paper reviewed the development of nanozymes and their application in virus detection,and introduced the current research progress of nanozymes to promote the wide application of nanozymes in medical diagnosis and treatment.By comparing the commonly used detection methods,some detection methods of nanozymes were presented.The new detection technology and methods based on the characteristics of nanozymes were summarized,as well as their ideas and effects.Additionally,the remaining challenges and unsolved problems were also highlighted.Compared with natural enzymes,nanozymes have superior properties and play an increasingly important role not only in virus detection,but also in other fields such as biomedicine,environmental protection and disease treatment.With the further research on the properties and catalytic mechanism of nanozymes,more functional nanozymes will be designed and new fast and efficient detection techniques will be developed.

关 键 词：纳米酶 纳米材料 酶活性 高灵敏 病毒检测 催化机理 

分 类 号：Q81[生物学—生物工程]