甲泼尼龙琥珀酸钠致皮肤过敏反应  

Skin allergic reaction induced by methylprednisolone sodium succinate

作　　者：舒文琳[1] 陈水钫[1] Shu Wenlin;Chen Shuifang(Department of Pharmacy,Xiamen Hospital of Traditional Chinese Medicine,Fujian Province,Xiamen 361009,China)

机构地区：[1]厦门市中医院药学部,厦门361009

出　　处：《药物不良反应杂志》2020年第12期701-702,共2页Adverse Drug Reactions Journal

摘　　要：1例4岁7个月男孩因支气管肺炎合并支原体、病毒和细菌多重感染给予阿奇霉素0.16 g静脉滴注、1次/d,甲泼尼龙琥珀酸钠32 mg静脉滴注、1次/d和阿莫西林克拉维酸钾干混悬剂228.5 mg口服、2次/d。6 d后,患儿症状改善,体温恢复正常。治疗第7天,患儿出现皮疹伴瘙痒,对症治疗后当日可消退。停用阿莫西林克拉维酸钾和阿奇霉素,但患儿仍在每天静脉滴注药物后发疹并当日消退;停用甲泼尼龙琥珀酸钠,患儿皮疹未再发作。A 4 years and 7 months old boy was treated with IV infusions of azithromycin 0.16 g once daily and methylprednisolone sodium succinate 32 mg once daily and oral amoxicillin and clavulanate potassium for suspension 228.5 mg twice daily for bronchopneumonia complicated with multiple co‑infections with mycoplasma,viruses,and bacteria.After 6 days of treatments,the boy′s symptoms were improved and his body temperature returned to normal.On the 7th day of treatments,the boy developed rash with itching,which subsided on the same day after symptomatic treatments.Amoxicillin and clavulanate potassium and azithromycin were discontinued,but the child still developed rash every time after IV infusion of methylprednisolone sodium succinate,which could subside later that day.After withdrawal of methylprednisolone sodium succinate,the boy′s rash did not recur.

关 键 词：甲泼尼龙 药疹 过敏反应 

分 类 号：R969[医药卫生—药理学]