脉冲染料激光联合CO_(2)点阵激光治疗烧伤后增生性瘢痕疗效评价  

Evaluation on Curative Effect of Pulsed Dye Laser Combined with CO_(2) Fractional Laser on Hypertrophic Scar after Burn

作　　者：骆婧 宁金斌 赵红维 苏宁 康文雯 LUO Jing;NING Jin-bin;ZHAO Hong-wei;SU Ning;KANG Wen-wen(Department of Burn and Plastic Surgery,Air Force Military Medical University Second Affiliated Hospital Tangdu Hospital,Xi'an 710038,Shaanxi,China)

机构地区：[1]空军军医大学第二附属医院唐都医院烧伤整形科,陕西西安710038

出　　处：《中国美容医学》2020年第12期43-46,共4页Chinese Journal of Aesthetic Medicine

摘　　要：目的:探讨脉冲染料激光(PDL)联合CO2点阵激光治疗烧伤后增生性瘢痕的临床疗效。方法:选取2018年6月-2019年8月笔者医院收治的96例烧伤后增生性瘢痕患者为研究对象,随机分为观察组和对照组,每组48例。对照组采用CO2点阵激光治疗,观察组采用脉冲染料激光联合CO2点阵激光治疗,比较两组患者治疗6个月后的总有效率,治疗前后瘢痕厚度、瘢痕面积、温哥华瘢痕量表(VSS)评分、疼痛视觉模拟评分(VAS)、瘙痒数字评分(NRS),以及治疗期间不良反应发生率。结果:治疗后,观察组患者的总有效率明显高于对照组(P<0.05);观察组患者的瘢痕厚度、瘢痕面积、疼痛VAS评分、瘙痒NRS、VSS各项评分和总分均低于对照组(P<0.05);且两组患者在治疗期间的不良反应发生率比较无显著性差异(P>0.05)。结论:CO2点阵激光联合PDL治疗烧伤后增生性瘢痕可早期抑制血管过度增生,改善瘢痕大小、皮肤外观和疼痛瘙痒症状,提高临床疗效。Objective To explore clinical curative effect of pulsed dye laser(PDL)combined with CO2 fractional laser on hypertrophic scar after burn.Methods A total of 96 patients with hypertrophic scars after burn who were admitted to the hospital from June 2018 to August 2019 were enrolled as study objects.They were randomly divided into observation group and control group,48 cases in each group.The control group was treated with CO2 fractional laser,while observation group was treated with PDL combined with CO2 fractional laser.The total response rate after 6 months of treatment,scar thickness,scar area,scores of Vancouver Scar Scale(VSS),pain visual analogue scale(VAS)and numeric rating scale(NRS)before and after treatment,and incidence of adverse reactions during treatment were compared between the two groups.Results After treatment,total response rate in observation group was significantly higher than that in control group(P<0.05).The scar thickness,scar area,scores of pain VAS,pruritus NRS and VSS,and their total scores in observation group were lower than those in control group(P<0.05).There was no significant difference in incidence of adverse reactions during treatment period between the two groups(P>0.05).Conclusion CO2 fractional laser combined with PDL in treatment of hypertrophic scars after burn can early inhibit vascular hyperplasy,improve scar size,skin appearance and symptoms such as pain and itching,and improve clinical curative effect.

关 键 词：CO_(2)点阵激光 脉冲染料激光 增生性瘢痕 疗效 不良反应 瘙痒 

分 类 号：R619.6[医药卫生—外科学]