植物蛋白质翻译后修饰组学研究进展  

Advances in the Studies of Plant Protein Post-translational Modification

作　　者：刘静 李亚超 周梦岩 吴鹏飞[1,2] 马祥庆 李明[1,2] LIU Jing;LI Ya-chao;ZHOU Meng-yan;WU Peng-fei;MA Xiang-qing;LI Ming(College of Forestry,Fujian Agriculture and Forestry University,Fuzhou 350002;Fujian Cunninghamia lanceolata Germplasm Innovation and Industrialization Engineering Research Center,Fuzhou 350002)

机构地区：[1]福建农林大学林学院,福州350002 [2]福建省杉木种质创新及产业化工程研究中心,福州350002

出　　处：《生物技术通报》2021年第1期67-76,共10页Biotechnology Bulletin

基　　金：国家自然科学基金项目(31971674);福建农林大学科技创新专项基金(CXZX2019041G)。

摘　　要：蛋白质翻译后修饰(Protein post-translational modification,PTMs)是一种重要的细胞调控机制,通过在蛋白质的氨基酸侧链上共价结合一些化学小分子基团来调节蛋白质的活性、结构、定位和蛋白质间的互作关系,从而精细调控蛋白质生物学功能的动态变化。PTMs是植物对环境变化最快、最早的反应之一,是植物蛋白质组多样性的关键机制,在植物生长发育和对环境适应中起重要作用。主要介绍了近年来植物磷酸化、乙酰化、琥珀酰化、糖基化、泛素化、巴豆酰化、S-亚硝基化及2-羟基异丁酰化等PTMs研究进展,旨为认识植物PTMs的关键生物学功能和研究前景提供参考。Protein post-translational modification(PTMs)is an important cellular regulatory mechanism.It regulates the activity,structure,positioning and interaction between proteins by covalently binding some chemical small molecular groups on the amino acid side chains of proteins,thereby fine-tuning the dynamic changes of protein’s biological functions.PTMs are one of the fastest and earliest responses of plants to environmental changes.They are the key mechanism of plant proteome diversity and play an important role in plant growth and development and environmental adaptation.This article mainly introduces the research progress of plant PTMs such as phosphorylation,acetylation,succinylation,glycosylation,ubiquitination,crotonylation,S-nitrosylation,2-hydroxyisobutylation,etc.in recent years,aiming to provide references for understanding the key biological functions and research prospects of plant PTMs.

关 键 词：翻译后修饰 蛋白质组 磷酸化 乙酰化 泛素化 

分 类 号：Q943[生物学—植物学]