湖北省健康人群麻疹免疫水平监测结果分析  

Analysis of monitoring results on measles immune level among healthy population in Hubei province

作　　者：骆金俊 熊伟胜 李婷婷 LUO Jin-jun;XIONG Wei-sheng;LI Ting-ting(Hubei Provincial Center for Disease Control and Prevention,Wuhan,Hubei 430079.China)

机构地区：[1]湖北省疾病预防控制中心,湖北武汉430079 [2]湖北省环境科学研究院 [3]武汉民政职业学院康复医疗学院

出　　处：《应用预防医学》2020年第6期472-475,共4页Applied Preventive Medicine

摘　　要：目的了解湖北省健康人群麻疹免疫水平,为制定麻疹预防控制策略提供依据。方法2015—2018年采用多阶段分层随机抽样方法,抽取湖北省13个县(市、区)健康人群共5998人开展麻疹抗体水平监测。采用酶联免疫吸附测定(ELISA)法测定麻疹抗体,运用卡方检验(χ^2)比较各组人群麻疹抗体阳性率。结果湖北省健康人群麻疹抗体总阳性率为87.06%。麻疹抗体阳性率在地区、性别、年龄、职业、免疫史、年份之间差异有统计学意义(P值均<0.05)。1岁以下散居儿童麻疹抗体阳性率相对较低(63.24%),未全程接种含麻类疫苗人群麻疹抗体阳性率相对较低(84.10%),鄂州市麻疹阳性率相对偏低(64.62%)。结论湖北省健康人群麻疹抗体水平总体维持在较高水平,提高重点人群(1岁以下散居儿童和未全程接种含麻类疫苗人群)和重点地区(鄂州市)麻疹疫苗接种率,有利于提高健康人群麻疹抗体阳性率,降低麻疹发病风险。ObjectiveTo understand the measles immune level among healthy population in Hubei province,provide the basis for the formulation of measles prevention and control strategy.MethodsFrom 2015 to 2018,a total of 5998 healthy people from 13 counties(cities and districts)in Hubei province were selected for the measles antibody level monitoring by multi-stage stratified random sampling method.Determination of measles antibody by enzyme-linked immunosorbent assay(ELISA),and the positive rate of measles antibody in each group was compared by chi-square(χ^2)test.ResultsThe positive rate of measles antibody was 87.06%in the healthy population of Hubei province.There were statistically significant differences in the positive rate of measles antibody among areas,genders,ages,occupations,immunization history,and years(all P values<0.05).The positive rate of measles antibody in family living children under 1-year-old was relatively low(63.24%),the positive rate of measles antibody in the people who had not been fully vaccinated with hempcontaining vaccine was relatively low(84.10%),and the positive rate of measles antibody in Ezhou city was relatively low(64.62%).ConclusionsThe level of measles antibody among healthy population in Hubei province maintains at a relatively high level.Improving the measles vaccination rate in key populations(family linving children under 1-year-old and those who have not been fully vaccinated with hemp-containing vaccines)and key areas(Ezhou city)is beneficial to increase the positive rate of measles antibody among healthy people and reduce the risk of measles.

关 键 词：麻疹 免疫水平 监测 健康人群 

分 类 号：R511.1[医药卫生—内科学]