瓣膜疾病相关巨大左室的外科术前评估研究进展  

Research progress on the presurgical evaluation of giant left ventricle associated with valvular disease

作　　者：牛昊 肖正华[1] NIU Hao;XIAO Zhenghua(Department of Cardiovascular Surgery,West China Hospital,Sichuan University,Chengdu,610041,P.R.China)

机构地区：[1]四川大学华西医院心脏大血管外科,成都610041

出　　处：《中国胸心血管外科临床杂志》2021年第1期116-121,共6页Chinese Journal of Clinical Thoracic and Cardiovascular Surgery

基　　金：四川省科技厅重点研发项目(2018SZ0384);四川大学华西医院横向课题(HX-H1709108)。

摘　　要：心脏瓣膜疾病由于瓣膜结构以及功能异常,逐渐出现左心室内径及容积的扩大,当左室舒张末期内径及容积严重扩张,即巨大左室。外科瓣膜置换手术仍是该类疾病的主要治疗方式之一,术后心室缩小程度与围手术期死亡率以及远期预后密切相关。但目前临床已有的术前评估方法仍无法准确预测此类患者术后左心室缩小程度以及远期预后,从而难以确定患者最佳手术时机以及手术方式。因此,我们对已有文献进行综述,探讨对于术前巨大左室的不同评估手段,以期优化此类患者围手术期治疗方式,明确手术时机,改善预后。Due to the abnormal structure and function of the cardiac valves,cardiac valve disease gradually appears the expansion of left ventricular inner diameter and volume.When the left ventricular end-diastolic dimension and volume expand severely,it becomes a giant left ventricle.Surgical valve replacement is still one of the main treatment methods for this disease.The degree of postoperative ventricular recovery is closely related to perioperative mortality and long-term prognosis.However,the existing clinical preoperative assessment methods still cannot accurately predict the degree of postoperative left ventricular recovery and long-term prognosis of such patients,so it is difficult to determine the optimal operation timing and surgical methods for patients.Therefore,we reviewed the existing literature and discussed different evaluation methods of the giant left ventricle associated with valvular disease before surgery,so as to optimize the perioperative treatment of such patients,clarify the timing of surgery and improve the prognosis.

关 键 词：巨大左室 心肌纤维化 循环标志物 超声心动图 心脏磁共振成像 

分 类 号：R654.2[医药卫生—外科学]