碳水化合物交换份法饮食干预对新发糖耐量异常患者的疗效  

Efficacy of food exchange portion of carbohydrate in patients with newly-diagnosed impaired glucose tolerance

作　　者：周建英[1] 黄益倩 沈晓明 束龙[2] 章小艳 郑培奋[1] ZHOU Jianying;HUANG Yiqian;SHEN Xiaoming;SHU Long;ZHANG Xiaoyan;ZHENG Peifen(Department of Digestion and Nutrition,Zhejiang Hospital,Hangzhou 310013,China)

机构地区：[1]浙江医院消化内科,杭州310013 [2]浙江医院临床营养科,杭州310013 [3]浙江医院平湖分院(平湖市第一人民医院)内分泌科

出　　处：《浙江医学》2021年第1期60-63,共4页Zhejiang Medical Journal

基　　金：浙江省卫生厅培育项目(2014PYA002)。

摘　　要：目的探讨碳水化合物交换份法对新发糖耐量异常(IGT)患者的疗效。方法选取2014年7月至2018年12月浙江医院内分泌科(中美糖尿病中心)及浙江医院平湖分院内分泌科收治的新发IGT患者91例,随机分为实验组(47例)和对照组(44例)。对照组患者给予常规的饮食宣教;实验组患者在对照组基础上给予碳水化合物交换份法的饮食干预:(1)IGT患者的常规饮食宣教;(2)针对IGT患者,通过碳水化合物交换份法表配制的针对性营养餐。临床干预3个月,每月随访1次,比较干预前后两组IGT患者的FPG、餐后2 h血糖(2hPG)、糖化血红蛋白(HbA1C)、TG、TC、HDL-C、LDL-C、血尿酸(SUA);观察两组患者干预期间不良事件的发生情况。结果干预后,实验组患者FPG、2hPG、HbA1C、TG、LDL-C及SUA较干预前均明显降低(均P<0.05);与干预前比较,对照组患者干预后HbA1C和SUA均明显降低(均P<0.05)。干预后,实验组患者FPG、2hPG、HbA1C、TG、LDL-C及SUA均明显低于对照组(均P<0.05)。干预后实验组患者的低血糖及严重乏力发生率与对照组比较差异均无统计学意义(均P>0.05)。结论碳水化合物交换份法对改善IGT患者的血糖、HbA1C水平,具有明显的效果。Objective To evaluate the efficacy of food exchange portion of carbohydrate in patients with newly-diagnosed impaired glucose tolerance(IGT).Methods Ninety one patients with newly-diagnosed IGT were enrolled in the Department of Endocrinology of Zhejiang Hospital(Sino-American Diabetes Center)and the Department of Endocrinology of Pinghu Branch of Zhejiang Hospital from July 2014 to December 2018.Patients were randomly divided into experimental group(47 cases)and control group(44 cases).Patients in control group received the regular dietary education;On the basis of the control group,patients in study group received the dietary intervention with food exchange portion of carbohydrate:(1)regular dietary education of IGT patients,(2)targeted nutritional meals prepared by carbohydrate exchange share method for IGT patients.The clinical intervention lasted for 3 months,and the patients were followed up once a month.The fasting blood glucose(FPG),2-h postprandial blood glucose(2hPG),HbA1C and other biochemical indicators were determined before and after the intervention.The adverse events during the intervention period were observed in two groups.Results After the intervention,the HbA1C,FPG,2hPG,TG,TC,LDL-C and SUA in study group were significantly decreased compared with those before the diet intervention(all P<0.05).Compared with before intervention,HbA1C and SUA in the control group were significantly decreased after the intervention(both P<0.05).Compared with the control group,the above indicators in the study group showed significant reduction after intervention(all P<0.05).There was no significant difference in the occurrence of hypoglycemia and severe fatigue after the intervention between two groups(all P>0.05).Conclusion The food exchange portion of carbohydrate has significant efficacy in improving blood glucose and HbA1C level in IGT patients.

关 键 词：碳水化合物交换份法 饮食干预 糖耐量异常 

分 类 号：R587.1[医药卫生—内分泌]