抗MDA5抗体阳性重症皮肌炎1例  

A Case of Severe Dermatomyositis with Anti-MDA5 Antibody Positive

作　　者：陈文文 夏育民[1] CHEN Wenwen;XIA Yumin(Department of Dermatology,the Second Affiliated Hospital,Xi'an Jiaotong University,Xi'an 710004,China)

机构地区：[1]西安交通大学第二附属医院皮肤科,陕西西安710004

出　　处：《中国皮肤性病学杂志》2021年第1期83-86,共4页The Chinese Journal of Dermatovenereology

摘　　要：患者女,31岁,多发肌肉疼痛4个月,咳嗽、气短2个月,发热3 d。肌电图提示肌炎活动期;特发性炎性肌炎谱示:抗MDA5抗体IgG(3+),抗Ro-52抗体IgG(3+);胸部CT提示两肺间质性改变及感染。诊断:皮肌炎,肺间质病变,Ⅰ型呼吸衰竭,肺部感染。A 31-year-old female presented multiple muscle pain for four months,cough and shortness of breath for two months,and fever for three days.Electromyogram indicated the active phase of myositis.Idiopathic inflammatory myositis spectrum:anti-MDA5 antibody IgG(3+),anti-Ro-52 antibody IgG(3+).CT scan of the lung revealed pulmonary interstitial change and infection.The diagnosis was dermatomyositis,interstitial lung disease,typeⅠrespiratory failure,pulmonary infection.

关 键 词：皮肌炎 肺间质病变 抗MDA5抗体 

分 类 号：R593.26[医药卫生—内科学]