PAMPS-G/C强韧性自修复水凝胶的制备及性能研究  

Development and Performance Study of PAMPS-G/C Tough and Self-healing Hydrogel

作　　者：张浩 张全元[1] 徐祖顺[1] ZHANG Hao;ZHANG Quan-yuan;XU Zu-shun(School of Material Science and Engineering,Hubei University,Wuhan 430062)

机构地区：[1]湖北大学材料科学与工程学院,武汉430062

出　　处：《胶体与聚合物》2020年第4期153-156,共4页Chinese Journal of Colloid & Polymer

摘　　要：通过磺胺化反应制备了一系列鸟嘌呤(G)和胞嘧啶(C)接枝的聚(2-丙烯酰胺-2-甲基丙磺酸)聚合物PAMPS-G及PAMPS-C。利用鸟嘌呤和胞嘧啶之间的碱基对氢键作用,制备了具有粘附性及自修复性能的PAMPS-G/C复合水凝胶。利用红外光谱(FT-IR)、核磁、扫描电镜(SEM)和拉力测试对水凝胶性能进行分析测试。结果表明:引入鸟嘌呤和胞嘧啶可以赋予水凝胶材料优异的自修复性能、生物相容性和粘附性能。调控碱基的含量可改善水凝胶的拉伸强度、自修复性能及粘附能力。其拉伸强度可达122 KPa,自修复效果可达到65%。因此,该水凝胶材料在伤口敷料和可穿戴设备等生物医学材料具有非常好的潜在应用价值。A series of guanine and cytosine grafted poly(2-acrylamide-2-methylpropylsulfonic acid)polymers PAMPS-G and PAMPS-C were prepared by sulfonation reaction. By mixing different contents of PAMPS-G and PAMPS-C, using the base-pair hydrogen bonding between guanine and cytosine, a PAMPS-G/C composite hydrogel with tissue adhesion and self-healing properties was prepared. The properties of PAMPS-G/C hydrogels were analyzed and tested by FT-IR, nuclear magnetic resonance,scanning electron microscope and tensile test. The results show that the introduction of guanine and cytosine can give the hydrogel material excellent self-healing properties, biocompatibility and adhesion properties.Adjusting the content of bases can effectively improve the tensile strength, self-repair performance and adhesion ability of the hydrogel. Its tensile strength can reach 122 KPa, and the self-repairing effect can reach 65% of the original. Therefore, the hydrogel material has very good potential application value in biomedical materials such as wound dressings and wearable devices.

关 键 词：粘性 自修复 水凝胶 碱基对 

分 类 号：O631[理学—高分子化学]