五味子在骨重建中作用机制的研究进展  

Advances in the mechanism of action of schisandra chinensis in bone remodeling

作　　者：姜南希 王珏[1] 王倩[1] 杨楠[1] 吴佳 李凌锋[1] 张骁 刘志辉[1] Jiang Nanxi;Wang Jue;Wang Qian;Yang Nan;Wu Jia;Li Lingfeng;Zhang Xiao;Liu Zhihui(Department of Prosthodontics,School and Hospital of Stomatology,Jilin University,Changchun 130021,China)

机构地区：[1]吉林大学口腔医学院修复科,长春130021

出　　处：《中华口腔医学杂志》2020年第12期1011-1015,共5页Chinese Journal of Stomatology

基　　金：吉林省科技发展计划(20190304032YY,20180201056YY)。

摘　　要：五味子是一种应用广泛的中药,可维持骨重建平衡,在促进成骨细胞分化、调控破骨细胞活性以及软骨保护等方面有重要作用,为骨质疏松、骨关节炎等疾病的治疗提供广阔前景。本文综述五味子及其活性成分在骨重建中的作用机制,以期为其产品开发及在骨组织工程中的应用提供理论依据。Schisandra is a widely used herb in traditional Chinese medicine.It can maintain the balance of bone reconstruction and play an important role in promoting osteoblast differentiation,regulating osteoclast activity and protecting cartilage tissue.It provides a broad prospect for the treatment of osteoporosis,osteoarthritis and some other diseases.In this paper,the action mechanism of schisandra chinensis and its active components in bone reconstruction was reviewed in order to provide theoretical basis for its product development and application in bone tissue engineering.

关 键 词：五味子属 骨重建 成骨细胞 破骨细胞 

分 类 号：R285[医药卫生—中药学]