泛耐药铜绿假单胞菌感染的抗感染思路分析  

Analysis of anti-infection of pneumonia caused by extensively drug resistant Pseudomonas aeruginosa

作　　者：池婕 Chi Jie(Tongling Municipal Hospital,Tongling 244000)

机构地区：[1]铜陵市立医院,铜陵244000

出　　处：《中国抗生素杂志》2020年第11期1182-1185,共4页Chinese Journal of Antibiotics

摘　　要：目的探讨泛耐药铜绿假单胞菌肺炎的药物治疗方案。方法以临床药师参与一例大面积烧伤患者的泛耐药铜绿假单胞菌肺炎的抗感染方案为例,结合最新临床研究进展,探讨抗菌药物雾化吸入在治疗泛耐药细菌导致的肺部感染中的应用。结果泛耐药铜绿假单胞菌导致的肺部感染通常选择联合治疗,抗菌药物雾化吸入作为一种联合或补充治疗,可以提高肺部药物浓度,减少全身不良反应,但使用时仍需慎重选择临床适应症。结论临床药师应积极参与抗感染方案的制定,针对患者制定个体化的给药方案。Objective To discuss the antimicrobial treatment of extensively drug resistant Pseudomonas aeruginosa infections. Methods A successful anti-infection control case of pneumonia caused by extensively drug resistant Pseudomonas aeruginosa with participation of clinical pharmacists was reported. The results were analyzed to formulate anti-infection treatment strategy combined with clinical practice and the latest literatures. Results The combination of antibiotic drugs was essential according to clinical guidelines and experiments. Aerosol inhalation of antibiotic which should be used carefully was an effective way to increase the concentration of drugs in lung, and decrease the incidence of adverse reactions. Conclusion Clinical pharmacists should actively take part in the optimization of anti-infection program.

关 键 词：泛耐药铜绿假单胞菌 肺部感染 雾化吸入 

分 类 号：R978.1[医药卫生—药品]