多层螺旋CT结合血清hs-cTnT、BNP、hs-CRP检测早期诊断急性冠脉综合征的临床研究  

Clinical Research of Multi-slice Spiral CT Combined with Serum Hs cTnT,BNP and Hs-CRP Detection for Early Diagnosis of Acute Coronary Syndrome

作　　者：朱钜铭 李相雁 周芳 黄思兵[4] ZHU Ju-ming;LI Xiang-yan;ZHOU Fang(Department of Laborator,Huizhou First People's Hospital,Huizhou,Guangdong,516003,China)

机构地区：[1]惠州市第一人民医院检验科,广东惠州516003 [2]惠州市第一人民医院放射科,广东惠州516003 [3]惠州市中心人民医院输血科,广东惠州516000 [4]惠州市第一人民医院心血管内科,广东惠州516003

出　　处：《黑龙江医学》2021年第1期24-26,共3页Heilongjiang Medical Journal

摘　　要：目的:探究多层螺旋CT结合血清hs-cTnT、BNP、hs-CRP检测在急性冠状动脉综合征早期诊断中的临床应用价值。方法:回顾性分析2018年11月-2019年11月惠州市第一人民医院胸痛中心收治的120例急性冠脉综合征患者的临床资料,根据病理类型不同分为ST段抬高型急性心肌梗死(STEMI)组(n=40)、非ST段抬高型急性心肌梗死(NSTEMI)组(n=40)、不稳定型心绞痛(UAP)组(n=40),另选同期40例非器质性心脏病变患者为对照组,四组均接受血清hs-cTnT、BNP、hs-CRP检测,以及多层螺旋CT心脏检查,比较不同组别上述检查结果的差异。结果:(1)以冠脉造影为标准,多层螺旋CT心脏检查诊断急性冠脉综合征患者冠状动脉无狭窄、轻度狭窄、中度狭窄、重度狭窄的准确率依次为95.65%、79.70%、82.91%、85.19%。(2)STEMI组、NSTEMI组、UAP组、对照组之间的hs-cTnT、BNP、hs-CRP水平有明显的差异(P<0.05)。结论:将CT检查与血清hs-cTnT、BNP、hs-CRP检测联合应用,便于临床准确诊断急性冠脉综合征并评估患者的病情严重程度,为临床治疗提供依据。Objective:To explore the clinical value of multi-slice spiral CT combined with serum hs-cTnT,BNP and hs-CRP detection in the early diagnosis of acute coronary syndrome.Methods:The clinical data of 120 patients with acute coronary syndrome were retrospectively analyzed.According to different pathological types,they were divided into ST-segment elevation acute myocardial infarction STEMI group(n=40),non-ST-segment elevation acute myocardial infarction NSTEMI group(n=40)and unstable angina pectoris UAP group(n=40).In addition,40 patients with non-organic heart disease during the same period were selected as the control group.All four groups received serum hs-cTnT,BNP,hs-CRP detection and multi-slice spiral CT cardiac examination.The examination differences of different groups were compared.Results:The accuracy of multislice spiral CT cardiac examination in the diagnosis of coronary artery stenosis in patients with acute coronary syndrome was 95.65%,mild stenosis was 79.70%,moderate stenosis was 82.91%,and severe stenosis was 85.19%.The levels of hs-cTnT,BNP and hs-CRP in four groups were significantly different(P<0.05).Conclusion:The combination of CT and hs-cTnT,BNP,hs-CRP can accurately diagnose the pathological type and the degree of coronary stenosis of ACS,and provide the basis for clinical treatment.

关 键 词：急性冠脉综合征 多层螺旋CT 高敏心肌肌钙蛋白T 脑钠肽 超敏C反应蛋白 

分 类 号：R331.31[医药卫生—人体生理学]