金属有机框架:用于功能性表面增强拉曼散射  

Metal-organic frameworks: For functional surface enhancement Raman scattering

作　　者：高俊 田洋[1] 李中峰[1] 张琦萌 李响 肖絮 张卓勇[1] 张欣[1] Jun Gao;Yang Tian;Zhongfeng Li;Qimeng Zhang;Xiang Li;Xu Xiao;Zhuoyong Zhang;Xin Zhang(Department of Chemistry,Capital Normal University,Beijing 100048,China)

机构地区：[1]首都师范大学化学系,北京100048

出　　处：《科学通报》2020年第35期4027-4036,共10页Chinese Science Bulletin

基　　金：国家自然科学基金(21705112);北京市教育委员会科学研究项目(KM201710028009,KM201910028014);北京市优秀人才培养资助青年骨干个人项目(2017000020124G081);首都师范大学青年创新团队(009175301300)资助。

摘　　要：表面增强拉曼散射(surface-enhanced Raman scattering, SERS)光谱具有高灵敏性、高选择性等优点,能够克服传统拉曼光谱在表面科学和痕量分析中灵敏度低等问题,被应用到生物、食品、环境等领域,为结构表征、物质相互作用和化学反应机理的解释提供了不可或缺的信息.但是SERS基底制备难度大、操作耗时、重复性差等问题制约了表面增强拉曼散射的进一步应用.金属有机框架(metal-organic frameworks, MOF)是一种新型的多孔材料,具有超高孔隙率、极大比表面积、结构多样、易功能化等特性,近年来人们探索将其应用于表面增强拉曼散射中,以实现对特定领域体系中微量乃至痕量成分检测.本文从MOF材料用于SERS不同类型基底的制备出发,讨论了包括MOF单独作为SERS基底、在MOF的外表面固定纳米粒子、在MOF内部嵌入金属粒子、MOF用于核壳结构和MOF用于整合功能单元作为SERS基底等基底制备方法,总结了MOF用于SERS基底的合成策略及增强效果;介绍了当前MOF材料在SERS实际应用领域检测中的研究进展,同时阐明了目前MOF在SERS领域的应用中存在的问题,并对未来此技术的应用领域和发展前景进行展望.Surface enhanced Raman scattering has been applied in many fields such as biology, food, environmental analysis owing to its high-sensitivity reading "fingerprint" characteristics in the collected Raman spectra, and provide important information for structure characterization, material interaction and chemical reaction mechanism. SERS have many advantages like highly sensitive, accurate, fast and noninvasive, while substrate material is one of the key factors to improve the performance of SERS. However, due to the difficulty of substrate preparation, time-consuming operation, and poor repeatability, new technologies are urgently developed to break through the bottleneck. Metal organic framework is a new porous material with the characteristics of ultra-high porosity, maximum specific surface area, diversified structure and easy functionalization, etc. In recent years, people have applied it to surface enhanced Raman scattering spectroscopy to detect trace compounds. In this paper, different methods of MOF for SERS substrate preparation and different fields of SERS detection are introduced. Combining MOF and SERS techniques provides a new direction for testing methods and material applications. Reasonable design and preparation of MOF body can precisely control the structure of the substrate,so as to optimize the substrate performance, such as adsorption performance, signal strength, stability, reproducibility and biocompatibility. In addition, this method provides a simple and powerful way to manufacture alternative substrates, which will stimulate innovative applications in the field of traditional technical methods and materials.We first introduced the preparation of different MOF substrates of SERS, including solo MOF as a SERS substrate,fixing nanoparticles on the surface of MOF, embedding metal nanoparticles inside MOF, core-shell structure based on MOF and MOF for integrating functional units as Reinforcement substrate. We also summarized the synthesis strategy and enhancement effect of MOF for SERS substra

关 键 词：金属有机框架 表面增强拉曼散射 表面增强拉曼散射基底 表面增强拉曼散射检测 复合材料 

分 类 号：O657.37[理学—分析化学] O641.4[理学—化学]