泡沫铜无溶剂催化氧化苄醇的应用研究  

Copper foam-catalyzed solvent-free aerobic oxidation of benzylic alcohol

作　　者：马佳美 张淑华[1] 钟伟[2] 沈忠权 MA Jia-mei;ZHANG Shu-hua;ZHONG Wei;SHEN Zhong-quan(College of Chemistry and Bioengineering,Guilin University of Technology,Guilin 541000,China;College of Biological,Chemical Sciences and Engineering,Jiaxing University,Jiaxing 314001,China)

机构地区：[1]桂林理工大学化学与生物工程学院,广西桂林541000 [2]嘉兴学院生物与化学工程学院,浙江嘉兴341001

出　　处：《化学研究与应用》2021年第1期129-136,共8页Chemical Research and Application

基　　金：嘉兴市科技计划项目(2018AY11003)资助。

摘　　要：本文报道了在模拟的鼓泡床反应器中,以1-甲基咪唑(NMI)和2,2,6,6-四甲基-1-哌啶基氧基(TEMPO)作为助催化剂,空气泵鼓入空气作为氧源,泡沫铜作为催化剂,室温、无溶剂条件下催化氧化苄醇的应用研究。具体优化条件为:以50 mmol苯甲醇为反应底物,2.5 mmol泡沫铜,0.625 mmol NMI,2.5 mmol TEMPO,空气流速300mL·min-1,室温无溶剂条件下反应6小时,苯甲醛产率达99%以上,并且催化剂在经过6次循环使用后产率仍然达82%。The efficient oxidation of benzylicalcohol using copper foam as the catalyst in a solvent-free and ambient condition was reported,in which a simulated bubble bed reactor was used via pump blows air as an oxygen source and employed NMI and TEMPO as cocatalyst.The specific optimization conditions were:50 mmol of benzyl alcohol,2.5 mmol of copper foam,0.625 mmol of NMI,2.5 mmol of TEMPO,300mL·min^-1 of air velocity,6 h for reaction time and more than 99%yield of benzaldehyde.Furthermore,the product yield could achieve 82%after 6 recycles of copper foam.

关 键 词：醇氧化 无溶剂 泡沫铜 鼓泡床反应器 

分 类 号：O614.12[理学—无机化学]