辽宁省盘锦市12例新型冠状病毒肺炎的临床转归分析  

Prognosis analysis of 12 patients with COVID-19 in Panjin City,Liaoning Province

作　　者：李环[1] 徐健峰[1] 孙晓丽[1] 姚启哲[1] 郭微 齐红霞[1] 孙畅 LI Huan;XU Jian-feng;SUN Xiao-li;YAO Qi-zhe;GUO Wei;QI Hong-xia;SUN Chang(Panjin Center for Disease Control and Prevention,Panjin,Liaoning 124010,China)

机构地区：[1]盘锦市疾病预防控制中心,辽宁盘锦124010

出　　处：《上海预防医学》2020年第11期918-921,共4页Shanghai Journal of Preventive Medicine

摘　　要：【目的】分析辽宁省盘锦市12例新型冠状病毒肺炎(COVID-19)病例的发病特征、新型冠状病毒(SARS-CoV-2)核酸转阴时间,了解出院后核酸复阳的影响因素。【方法】回顾性分析盘锦市12例COVID-19病例的临床表现、实验室检查及影像学检查,对病例SARS-CoV-2核酸转阴时间、核酸复阳情况进行相关性分析。【结果】12例COVID-19病例临床症状以发热(9/12)及呼吸道症状(8/12)为主,淋巴细胞降低者4例,影像学诊断肺炎病例11例,2例病例出院1周内鼻咽/肛拭子SARS-CoV-2核酸检测再次阳性。病例核酸转阴时间8~53 d、中位时间24.5 d,分析相关因素中影像学提示肺炎、病例来源于就诊和复阳是影响因素。【结论】COVID-19的临床转归个体差异较大、相关影响因素较多。应当引起足够的重视,防止疫情蔓延。[Objective]The characteristics of coronavirus disease 2019(COVID-19)were analyzed in 12 cases,including time of negative conversion of SARS-CoV-2 RNA and risk factors associated with testing re-positive for SARS-CoV-2 RNA after the discharge.[Methods]A total of 12 patients with COVID-19 in Panjin were collected.Clinical features,laboratory testing,and imaging examination of the patients were retrospectively studied.Moreover,the correlation between the time of negative conversion of SARS-CoV-2 RNA and testing re-positive after the discharge were determined.[Results]The clinical symptoms of 12 COVID-19 cases were mainly fever(9/12)and respiratory symptoms(8/12).In addition,there was lymphocyte reduction in 4 cases,imaging diagnosis of pneumonia in 11 cases,and 2 cases testing re-positive for SARS-CoV-2 RNA in the nasal pharyngeal/anal swab within 1 week of discharge.The time of negative conversion in the cases was 8-53 days,and the median time was 24.5 days.Imaging demonstrating the pneumonia,the case coming from the hospital visit,and testing re-positive for SARS-CoV-2 RNA were the risk factors.[Conclusion]Prognosis and its risk factors vary in the influencing factors of COVID-19 cases.It warrants more attention to prevent the spread of COVID-19.

关 键 词：新型冠状病毒肺炎 新型冠状病毒 核酸转阴时间 

分 类 号：R183.3[医药卫生—流行病学]