BiPAP无创通气辅治对重度子痫前期合并AHF患者血气分析指标及预后的影响  

Effects of BiPAP non-invasive ventilation auxiliary therapy on blood gas analysis indexes and prognosis of patients with severe preeclampsia and acute heart failure

作　　者：冯思思 常亮 FENG Si-si;CHANG Liang(Department of Obstetrics and Gynecology,Shaanxi Fourth People's Hospital,Xi'an 710043,Shaanxi,CHINA;Department of Emergency,Xi'an International Medical Center Hospital,Xi'an 710100,Shaanxi,CHINA)

机构地区：[1]陕西省第四人民医院妇产科,陕西西安710043 [2]西安国际医学中心医院急诊科,陕西西安710100

出　　处：《海南医学》2021年第1期75-78,共4页Hainan Medical Journal

摘　　要：目的探讨双水平气道正压(BiPAP)无创通气辅治对重度子痫前期(SPE)合并急性心力衰竭(AHF)患者血气分析指标和预后的影响。方法回顾性分析2017年5月至2019年5月陕西省第四人民医院收治的140例SPE合并AHF患者的临床资料,根据是否使用BiPAP无创通气辅助治疗将其分为对照组66例(未使用BiPAP无创通气辅助治疗)和观察组74例(使用BiPAP无创通气辅助治疗)。比较两组患者的年龄、孕周、胎次、血气分析指标[pH值、血氧分压(PaO2)、血二氧化碳分压(PaCO2),血氧饱和度(SaO2)]、临床症状(呼吸困难、肺啰)改善情况、住院时间、产科并发症及围生儿结局等。结果治疗后,观察组患者的PaO2、PaCO2、SaO2指标分别为(88.96±5.16)mmHg、(39.06±3.15)mmHg、(96.72±2.34)%,明显优于对照组的(79.18±5.82)mmHg、(47.67±3.81)mmHg、(92.56±2.49)%,差异均有统计学意义(P<0.05);治疗后,观察组患者呼吸困难减轻及肺啰音消失比率分别为97.30%、50.00,明显高于对照组的84.85%、33.33%,且观察组患者的住院时间为(10.68±0.92)d,明显短于对照组的(11.44±1.03)d,差异均有统计学意义(P<0.05);观察组患者出现产后出血、胎儿窘迫及新生儿窒息的总发生率为16.22%,明显低于对照组的30.30%,差异有统计学意义(P<0.05)。结论BiPAP无创通气辅治能有效改善SPE合并AHF患者血气分析指标及预后。Objective To explore the effects of bi-level positive airway pressure(BiPAP)non-invasive ventilation auxiliary therapy on blood gas analysis indexes and prognosis of patients with severe preeclampsia(SPE)and acute heart failure(AHF).Methods The clinical data of 140 patients with SPE and AHF,who admitted to Shaanxi Fourth People's Hospital from May 2017 to May 2019,were retrospectively analyzed.According to presence or absence of Bi-PAP non-invasive ventilation auxiliary therapy,they were divided into the control group(66 cases,no any treatment)and observation group(74 cases,BiPAP non-invasive ventilation auxiliary therapy).The age,gestational week,parity,blood gas analysis indexes pH value,partial pressure of oxygen[PaO2],partial pressure of carbon dioxide[PaCO2],oxygen saturation[SaO2],improvement of clinical symptoms(dyspnea,lung rales),hospitalization time,obstetric complications and outcomes of perinatal infants were compared between the two groups.Results After treatment,PaO2,PaCO2,and SaO2 in the observation group were(88.96±5.16)mmHg,(39.06±3.15)mmHg,(96.72±2.34)%,respectively,which were significantly better than corresponding(79.18±5.82)mmHg,(47.67±3.81)mmHg,(92.56±2.49)%in the control group(all P<0.05);the incidence rates of dyspnea remission and lung rales disappearance in observation group were 97.30%and 50.00%,which were significantly higher than corresponding 84.85%and 33.33%in control group,and hospitalization time was(10.68±0.92)d versus(11.44±1.03)d in control group(all P<0.05).The total incidence of postpartum hemorrhage,fetal distress,and neonatal asphyxia in the observation group was 16.22%,which was significantly lower than 30.30%in control group(P<0.05).Conclusion BiPAP non-invasive ventilation auxiliary therapy can effectively improve blood gas analysis indexes and prognosis of patients with SPE and AHF.

关 键 词：双水平气道正压无创通气 重度子痫前期 急性心力衰竭 血气分析 预后 

分 类 号：R714.245[医药卫生—妇产科学]