血流储备分数在冠心病特殊人群中的临床应用进展  

Clinical Application of Fractional Flow Reserve in Special Populations with Coronary Heart Disease

作　　者：赵航 汪立杰[1] 金元哲[1] ZHAO Hang;WANG Lijie;JIN Yuanzhe(The Fourth Affiliated Hospital of China Medical University,Shenyang 110000,Liaoning,China)

机构地区：[1]中国医科大学附属第四医院,辽宁沈阳110000

出　　处：《心血管病学进展》2020年第12期1272-1275,共4页Advances in Cardiovascular Diseases

摘　　要：尽管冠心病在治疗方面取得了一些进展,但它仍是全世界发病率和死亡率最高的疾病之一。冠状动脉血流储备分数测定是从功能学上评估冠状动脉病变的一种侵入性检测手段,其指导下的冠状动脉血运重建治疗可改善患者的临床预后。目前,冠状动脉血流储备分数不仅在冠心病患者群中得到了广泛应用,其在冠心病特殊合并症患者及冠状动脉先天性解剖异常疾病中也具有指导作用。随着新兴技术的不断发展,基于CT血管成像的无创血流储备分数及定量血流分数逐渐进入临床应用中,有望取代充血性指标并越来越多地用于冠状动脉狭窄的功能性评估。相信血流储备分数日后会成为临床医师为患者选择最佳治疗方案的有力工具。Despite advances in therapy,coronary heart disease(CHD)remains the leading cause of morbidity and mortality worldwide.The measurement of fractional flow reserve(FFR)is an invasive standard test to identify coronary artery stenosis functionally.And FFR-guided coronary artery revascularization could improve the clinical outcomes of CHD patients.Currently,FFR has not only been widely used in CHD patients,but also provides reasonable direction in CHD patients with special complications and in conditions of congenital anomalous origin of the coronary artery.With the advances of emerging technologies,CT-derived fractional flow reserve and quantitative flow ratio have been applied in clinical environments and are expected to replace the invasive hyperemic indexes and be increasingly used in the functional evaluation of coronary artery stenosis.We believe that FFR will become the useful technique to help guide clinicians in making the best management decisions for patients.

关 键 词：血流储备分数 冠心病 冠状动脉肺动脉瘘 定量血流分数 

分 类 号：R541.4[医药卫生—心血管疾病]